XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. - Wikidata - awgldk - TriplyDB

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

http://www.wikidata.org/entity/Q40519913

about

The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control.ERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosis The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma Melanoma and the Unfolded Protein Response Cancer Microenvironment and Endoplasmic Reticulum Stress Response Hypoxia signaling pathways: modulators of oxygen-related organelles Hypoxic signaling during tissue repair and regenerative medicine The unfolded protein response in retinal vascular diseases: implications and therapeutic potential beyond protein folding Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseases Hypoxia and fungal pathogenesis: to air or not to air?Cancer stem cell metabolism: a potential target for cancer therapy Adipose tissue dysfunction and its effects on tumor metabolism Stress responses from the endoplasmic reticulum in cancer Tumor progression and the different faces of the PERK kinase MicroRNA-214 Is Upregulated in Heart Failure Patients and Suppresses XBP1-Mediated Endothelial Cells Angiogenesis Inflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologies The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group UPR-induced resistance to etoposide is downstream of PERK and independent of changes in topoisomerase IIα levels Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions Tumorigenic and Immunosuppressive Effects of Endoplasmic Reticulum Stress in Cancer Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate Inhibition of proliferation by PERK regulates mammary acinar morphogenesis and tumor formation.Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy.Genetic variation of promoter sequence modulates XBP1 expression and genetic risk for vitiligo.Hypoxia and the hypoxic response pathway protect against pore-forming toxins in C. elegans.Transcriptional regulation of VEGF-A by the unfolded protein response pathway.The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity.Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response.Latent factor analysis to discover pathway-associated putative segmental aneuploidies in human cancers.Structural determinants of PERK inhibitor potency and selectivity Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease.Stressed to death: targeting endoplasmic reticulum stress response induced apoptosis in gliomas.Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus.Functional RNA interference (RNAi) screen identifies system A neutral amino acid transporter 2 (SNAT2) as a mediator of arsenic-induced endoplasmic reticulum stress

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P2860

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

http://www.wikidata.org/entity/Q40519913

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

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type

label

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

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prefLabel

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

@en

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0008-5472.CAN-04-1606

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Cancer Research

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XBP1 is essential for survival under hypoxic conditions and is required for tumor growth

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Amato J Giaccia

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Ann-Hwee Lee

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Daniel Nelson

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Ester Hammond

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Hongbin Cao

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Kazutoshi Mori

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Laurie H Glimcher

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Nicholas C Denko

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Quynh-Thu Le

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5943-5947

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scholarly article

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10.1158/0008-5472.CAN-04-1606

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17

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64

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Albert C. Koong

Lorenzo Romero-Ramírez

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2004-09-01T00:00:00Z

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8370959

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