Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities
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The miRNA world of polyomavirusesMutational analysis of merkel cell carcinomaStrategies for Human Tumor Virus Discoveries: From Microscopic Observation to Digital Transcriptome SubtractionMerkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus.Phosphorylation of large T antigen regulates merkel cell polyomavirus replicationMalawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors.Natural history of polyomaviruses in men: the HPV infection in men (HIM) study.Large T and small T antigens of Merkel cell polyomavirus.The raccoon polyomavirus genome and tumor antigen transcription are stable and abundant in neuroglial tumorsResponse of Merkel cell polyomavirus-positive merkel cell carcinoma xenografts to a survivin inhibitor.Phosphorylation of Merkel cell polyomavirus large tumor antigen at serine 816 by ATM kinase induces apoptosis in host cells.The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.Tumorigenic activity of merkel cell polyomavirus T antigens expressed in the stratified epithelium of mice.A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence.Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation.Merkel Cell Polyomavirus Small T Antigen Induces Cancer and Embryonic Merkel Cell Proliferation in a Transgenic Mouse ModelExpression of the small T antigen of Lymphotropic Papovavirus is sufficient to transform primary mouse embryo fibroblasts.Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expressionFunctional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses.Merkel cell polyomavirus large T antigen disrupts host genomic integrity and inhibits cellular proliferation.Host DNA damage response factors localize to merkel cell polyomavirus DNA replication sites to support efficient viral DNA replication.High-affinity Rb binding, p53 inhibition, subcellular localization, and transformation by wild-type or tumor-derived shortened Merkel cell polyomavirus large T antigens.Epigenetic Dysregulation in Virus-Associated Neoplasms.Merkel cell polyomavirus infection and Merkel cell carcinoma.A Review of Functional Motifs Utilized by Viruses.RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells.Merkel cell polyomavirus and Merkel cell carcinoma.Spontaneous lung metastasis formation of human Merkel cell carcinoma cell lines transplanted into scid mice.The T antigen locus of Merkel cell polyomavirus downregulates human Toll-like receptor 9 expression.Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.Merkel Cell Polyomavirus: A New DNA Virus Associated with Human Cancer.Human Polyomaviruses: The Battle of Large and Small Tumor Antigens.Merkel cell carcinoma in the age of immunotherapy: Facts and hopes.Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC.
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P2860
Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities
@en
type
label
Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities
@en
prefLabel
Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities
@en
P2860
P50
P356
P1433
P1476
Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities
@en
P2093
James A DeCaprio
Jingwei Cheng
P2860
P304
P356
10.1128/JVI.00385-13
P407
P577
2013-03-20T00:00:00Z