Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.
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The Noscapine Chronicle: A Pharmaco-Historic Biography of the Opiate Alkaloid Family and its Clinical ApplicationsMicrotubule-binding agents: a dynamic field of cancer therapeutics.A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During DiseaseNoscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction.Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathwayAntitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer.Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer.Anticancer activity of Noscapine, an opioid alkaloid in combination with Cisplatin in human non-small cell lung cancer.Decreased therapeutic effects of noscapine combined with imatinib mesylate on human glioblastoma in vitro and the effect of midkine.Drugs that target dynamic microtubules: a new molecular perspectiveSecond generation benzofuranone ring substituted noscapine analogs: synthesis and biological evaluationA novel effect of Noscapine on patients with massive ischemic stroke: A pseudo-randomized clinical trialCYLD Regulates Noscapine Activity in Acute Lymphoblastic Leukemia via a Microtubule-Dependent Mechanism.Drug-resistant T-lymphoid tumors undergo apoptosis selectively in response to an antimicrotubule agent, EM011.Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the Apc(Min/+) mouse model.Metabolic map and bioactivation of the anti-tumour drug noscapine.FDG-PET imaging for the evaluation of antiglioma agents in a rat modelRat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas.Antifibrotic effects of noscapine through activation of prostaglandin E2 receptors and protein kinase A.Synergistic suppression of noscapine and conventional chemotherapeutics on human glioblastoma cell growth.Peloruside, laulimalide, and noscapine interactions with beta-tubulin.Enhanced noscapine delivery using uPAR-targeted optical-MR imaging trackable nanoparticles for prostate cancer therapy.Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis.ST-11: A New Brain-Penetrant Microtubule-Destabilizing Agent with Therapeutic Potential for Glioblastoma Multiforme.Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents.Non-aggregated protamine-coated poly(lactide-co-glycolide) nanoparticles of cisplatin crossed blood-brain barrier, enhanced drug delivery and improved therapeutic index in glioblastoma cells: in vitro studies.Synthesis and biological evaluation of N-substituted noscapine analogues.Effect of noscapine and vincristine combination on demyelination and cell proliferation in vitro.Determination of factors controlling the particle size and entrapment efficiency of noscapine in PEG/PLA nanoparticles using artificial neural networks.Relevance of an opioid, noscapine in reducing cystogeneses in rat experimental model of polycystic ovary syndrome.Stabilization of hyperdynamic microtubules is neuroprotective in amyotrophic lateral sclerosis.Formulation approaches to improving the delivery of an antiviral drug with activity against seasonal flu.Synergistic Anticancer Effect of Paclitaxel and Noscapine on Human Prostate Cancer Cell Lines.
P2860
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P2860
Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.
@en
type
label
Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.
@en
prefLabel
Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.
@en
P2093
P1476
Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.
@en
P2093
Brian Ciliax
Bruce H Wainer
David R Archer
Harish C Joshi
Jaren W Landen
Johnathan D Glass
Mingshen Wang
Thomas Davis
Vincent Hau
P304
P356
10.1158/1078-0432.CCR-04-0360
P407
P577
2004-08-01T00:00:00Z