Kaposi's sarcoma-associated herpesvirus-encoded viral interleukin-6 is secreted and modified differently than human interleukin-6: evidence for a unique autocrine signaling mechanism.
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KSHV: pathways to tumorigenesis and persistent infectionAbrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage displayMolecular biology of KSHV in relation to AIDS-associated oncogenesis.Human herpesvirus 8-encoded cytokines.Contribution of viral mimics of cellular genes to KSHV infection and disease.Interleukin-6 and new strategies for the treatment of cancer, hyperproliferative diseases and paraneoplastic syndromes.Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5.Structural requirements for gp80 independence of human herpesvirus 8 interleukin-6 (vIL-6) and evidence for gp80 stabilization of gp130 signaling complexes induced by vIL-6.Viral interleukin-6: role in Kaposi's sarcoma-associated herpesvirus: associated malignancies.Human herpesvirus 8 viral interleukin-6 interacts with splice variant 2 of vitamin K epoxide reductase complex subunit 1.Kaposi's sarcoma-associated herpesvirus promotes angiogenesis by inducing angiopoietin-2 expression via AP-1 and Ets1Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV-MCD) and the KSHV Inflammatory Cytokine Syndrome.Modulation of Immune System by Kaposi's Sarcoma-Associated Herpesvirus: Lessons from Viral Evasion Strategies.Kaposi's Sarcoma-Associated Herpesvirus Interleukin-6 Modulates Endothelial Cell Movement by Upregulating Cellular Genes Involved in Migration.Kaposi's sarcoma-associated herpesviral IL-6 and human IL-6 open reading frames contain miRNA binding sites and are subject to cellular miRNA regulation.Contribution of viral and cellular cytokines to Kaposi's sarcoma-associated herpesvirus pathogenesisIntracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6Determinants of secretion and intracellular localization of human herpesvirus 8 interleukin-6.Complex N-linked glycans on Asn-89 of Kaposi sarcoma herpes virus-encoded interleukin-6 mediate optimal function by affecting cytokine protein conformation.Mechanisms Associated with Activation of Intracellular Metabotropic Glutamate Receptor, mGluR5.IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.The role of Kaposi sarcoma-associated herpesvirus in the pathogenesis of Kaposi sarcoma.Interleukin-6-dependent growth in a newly established plasmablastic lymphoma cell line and its therapeutic targetsModulation of Kaposi's sarcoma-associated herpesvirus interleukin-6 function by hypoxia-upregulated protein 1.Sequences within the C Terminus of the Metabotropic Glutamate Receptor 5 (mGluR5) Are Responsible for Inner Nuclear Membrane Localization.Synergy between Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 and HIV-1 Nef protein in promotion of angiogenesis and oncogenesis: role of the AKT signaling pathway.Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling.Human Herpesvirus 8 Interleukin-6 Interacts with Calnexin Cycle Components and Promotes Protein Folding.Promotion of Endoplasmic Reticulum-Associated Degradation of Procathepsin D by Human Herpesvirus 8-Encoded Viral Interleukin-6.Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor.Human herpesvirus 8 interleukin-6 contributes to primary effusion lymphoma cell viability via suppression of proapoptotic cathepsin D, a cointeraction partner of vitamin K epoxide reductase complex subunit 1 variant 2.Role of human herpesvirus 8 interleukin-6-activated gp130 signal transducer in primary effusion lymphoma cell growth and viability.Human herpesvirus 8 viral interleukin-6 signaling through gp130 promotes virus replication in primary effusion lymphoma and endothelial cells.
P2860
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P2860
Kaposi's sarcoma-associated herpesvirus-encoded viral interleukin-6 is secreted and modified differently than human interleukin-6: evidence for a unique autocrine signaling mechanism.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Kaposi's sarcoma-associated he ...... autocrine signaling mechanism.
@en
type
label
Kaposi's sarcoma-associated he ...... autocrine signaling mechanism.
@en
prefLabel
Kaposi's sarcoma-associated he ...... autocrine signaling mechanism.
@en
P2860
P356
P1476
Kaposi's sarcoma-associated he ...... autocrine signaling mechanism.
@en
P2093
Mark B Meads
P2860
P304
51793-51803
P356
10.1074/JBC.M407382200
P407
P577
2004-07-16T00:00:00Z