High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs.
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Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brainEffects of specific multi-nutrient enriched diets on cerebral metabolism, cognition and neuropathology in AβPPswe-PS1dE9 miceCholesterol-modifying strategies for Alzheimer's disease.Effects of a disrupted blood-brain barrier on cholesterol homeostasis in the brain.The ins and outs of cholesterol in the vertebrate retina.ApoE and cholesterol in schizophrenia and bipolar disorder: comparison of grey and white matter and relation with APOE genotypeCognitive Impairment and Age-Related Vision Disorders: Their Possible Relationship and the Evaluation of the Use of Aspirin and Statins in a 65 Years-and-Over Sardinian PopulationCyclodextrin promotes atherosclerosis regression via macrophage reprogramming.Molecular mechanisms underlying the effects of statins in the central nervous system.Chronic pravastatin but not atorvastatin treatment impairs cognitive function in two rodent models of learning and memorySterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levelsCholesterol and apolipoprotein E in Alzheimer's disease.Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout MiceThyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans.Cholesterol: its regulation and role in central nervous system disorders.Cholesterol metabolism in the brain: importance of 24S-hydroxylation.Oxysterols and Alzheimer's disease.Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain.Statin inhibits kainic acid-induced seizure and associated inflammation and hippocampal cell death.Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts.Effect of onion and beet on plasma and liver lipids, platelet aggregation, and erythrocyte Na efflux in simvastatin treated hypercholesterolmic ratsCharacterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage.The effect of APOE genotype on brain levels of oxysterols in young and old human APOE epsilon2, epsilon3 and epsilon4 knock-in mice.The Role of Lipid Biomarkers in Major Depression.Prescription of lipophilic statins to Alzheimer's disease patients: some controversies to consider.Brain cholesterol metabolism, oxysterols, and dementia.Current management of delayed cerebral ischemia: update from results of recent clinical trials.Dietary intake of plant sterols stably increases plant sterol levels in the murine brain.Inhibition of neuronal cholesterol biosynthesis with lovastatin leads to impaired synaptic vesicle release even in the presence of lipoproteins or geranylgeraniol.A specific inhibitor of cholesterol biosynthesis, BM15.766, reduces the expression of beta-secretase and the production of amyloid-beta in vitro.Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammationSphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neuronsImpact of a multi-nutrient diet on cognition, brain metabolism, hemodynamics, and plasticity in apoE4 carrier and apoE knockout mice.Decreased prevalence of dementia associated with statins: a national population-based study.Enzyme blockade: a nonradioactive method to determine the absolute rate of cholesterol synthesis in the brain.The Impact of Statin and Angiotensin-Converting Enzyme Inhibitor/Angiotensin Receptor Blocker Therapy on Cognitive Function in Adults With Human Immunodeficiency Virus Infection.Plasma 4beta-hydroxycholesterol: an endogenous CYP3A metric?Reductions in cholesterol and synaptic markers in association cortex in mood disorders.Increased plant sterol and stanol levels in brain of Watanabe rabbits fed rapeseed oil derived plant sterol or stanol esters.
P2860
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P2860
High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
High doses of simvastatin, pra ...... erol synthesis in guinea pigs.
@en
type
label
High doses of simvastatin, pra ...... erol synthesis in guinea pigs.
@en
prefLabel
High doses of simvastatin, pra ...... erol synthesis in guinea pigs.
@en
P2093
P50
P1433
P1476
High doses of simvastatin, pra ...... terol synthesis in guinea pigs
@en
P2093
Bernhard Lindenthal
Dieter Lütjohann
Karin Thelen
Klaus von Bergmann Kv
Mark Stroick
Sandra Kühl
Thomas Bertsch
Ulla Andersson
P304
P356
10.1016/J.STEROIDS.2004.03.012
P577
2004-06-01T00:00:00Z