Constitutive endocytic cycle of the CB1 cannabinoid receptor.
about
Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathwayGhrelin receptor mutations--too little height and too much hunger.Visualizing odorant receptor trafficking in living cells down to the single-molecule levelThe hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intakeEndogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB1 among different membrane microenvironments.Dynamic imaging of cannabinoid receptor 1 vesicular trafficking in cultured astrocytesEffects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signallingVisualization of a functionally enhanced GFP-tagged galanin R2 receptor in PC12 cells: constitutive and ligand-induced internalizationReversible disruption of pre-pulse inhibition in hypomorphic-inducible and reversible CB1-/- mice.Altered surface trafficking of presynaptic cannabinoid type 1 receptor in and out synaptic terminals parallels receptor desensitization.Beta-arrestin-based Bret2 screening assay for the "non"-beta-arrestin binding CB1 receptor.Ligand-induced regulation and localization of cannabinoid CB1 and dopamine D2L receptor heterodimersΔ9-THC increases endogenous AHA1 expression in rat cerebellum and may modulate CB1 receptor function during chronic useRegulated exocytosis in astrocytic signal integration.Hydrophobic residues in helix 8 of cannabinoid receptor 1 are critical for structural and functional properties.Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery?Physical and functional interaction between CB1 cannabinoid receptors and beta2-adrenoceptorsCannabinoid-induced actomyosin contractility shapes neuronal morphology and growth.Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1 ubiquitylation, endocytosis, and functionEndocannabinoids prevent β-amyloid-mediated lysosomal destabilization in cultured neurons.Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIaThe cannabinoid type-1 receptor carboxyl-terminus, more than just a tail.(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl piperazine analogs.Regulation of CB1 cannabinoid receptor trafficking by the adaptor protein AP-3Rab11 function in Trypanosoma brucei: identification of conserved and novel interaction partners.Endocannabinoid tone versus constitutive activity of cannabinoid receptors.Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulationDiscovery of dual-action membrane-anchored modulators of incretin receptorsCB(1) cannabinoid receptors and their associated proteins.Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide.Regulation of G protein-coupled receptor export trafficking.Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activationFast modulation of μ-opioid receptor (MOR) recycling is mediated by receptor agonists.Constitutive cholesterol-dependent endocytosis of melanocortin-4 receptor (MC4R) is essential to maintain receptor responsiveness to α-melanocyte-stimulating hormone (α-MSH).Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization.Galanin decreases proliferation of PC12 cells and induces apoptosis via its subtype 2 receptor (GalR2).Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling.Rab7 silencing prevents μ-opioid receptor lysosomal targeting and rescues opioid responsiveness to strengthen diabetic neuropathic pain therapy.Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1).Computational Prediction and Biochemical Analyses of New Inverse Agonists for the CB1 Receptor
P2860
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P2860
Constitutive endocytic cycle of the CB1 cannabinoid receptor.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Constitutive endocytic cycle of the CB1 cannabinoid receptor.
@en
type
label
Constitutive endocytic cycle of the CB1 cannabinoid receptor.
@en
prefLabel
Constitutive endocytic cycle of the CB1 cannabinoid receptor.
@en
P50
P921
P356
P1476
Constitutive endocytic cycle of the CB1 cannabinoid receptor
@en
P2093
Jean Rossier
P304
36013-36021
P356
10.1074/JBC.M403990200
P407
P577
2004-06-21T00:00:00Z