about
Short-term environmental enrichment rescues adult neurogenesis and memory deficits in APP(Sw,Ind) transgenic miceCrtc1 activates a transcriptional program deregulated at early Alzheimer's disease-related stagesInduction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12Synthesis, brain antihypoxic activity and cell neuroprotection of 1-substituted-3,7-dimethylxanthines.Histamine H2-receptor antagonist ranitidine protects against neural death induced by oxygen-glucose deprivation.Soluble oligomers of amyloid-β peptide disrupt membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction.Delineating the factors and cellular mechanisms involved in the survival of cerebellar granule neurons.Ras protein activation is a key event in activity-dependent survival of cerebellar granule neurons.The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis.Polyamine uptake in cultured cerebellar granule neurons.Novel Regulation of the Synthesis of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus.Bone morphogenetic protein-6 promotes cerebellar granule neurons survival by activation of the MEK/ERK/CREB pathwayX-linked inhibitor of apoptosis protein negatively regulates neuronal differentiation through interaction with cRAF and Trk.Endogenous XIAP, but not other members of the inhibitory apoptosis protein family modulates cerebellar granule neurons survival.Histamine modulation of glutamate release from hippocampal synaptosomes.Blockade of nitric oxide synthesis by tyrosine kinase inhibitors in neurones.PACAP and C2-ceramide generate different AP-1 complexes through a MAP-kinase-dependent pathway: involvement of c-Fos in PACAP-induced Bcl-2 expression.Nurr1 protein is required for N-methyl-D-aspartic acid (NMDA) receptor-mediated neuronal survivalIntraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.Polyamine uptake is necessary for a normal biochemical maturation of astrocytes in culture.Activation of caspase-8 by tumour necrosis factor receptor 1 is necessary for caspase-3 activation and apoptosis in oxygen-glucose deprived cultured cortical cells.CRTC1 Function During Memory Encoding Is Disrupted in Neurodegeneration.Noradrenergic modulation of the motor response induced by long-term levodopa administration in Parkinsonian rats.Tetanus toxin H(C) fragment reduces neuronal MPP+ toxicity.Brief exposure to NMDA produces long-term protection of cerebellar granule cells from apoptosis.Estradiol facilitates neurite maintenance by a Src/Ras/ERK signalling pathway.BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.Contribution of caspase-mediated apoptosis to the cell death caused by oxygen-glucose deprivation in cortical cell cultures.C2-ceramide mediates cerebellar granule cells apoptosis by activation of caspases-2, -9, and -3.N-methyl-D-aspartate blocks activation of JNK and mitochondrial apoptotic pathway induced by potassium deprivation in cerebellar granule cells.Modulation of the motor response to dopaminergic drugs in a parkinsonian model of combined dopaminergic and noradrenergic degeneration.17beta-estradiol does not protect cerebellar granule cells from excitotoxicity or apoptosis.beta-Amyloid disrupts activity-dependent gene transcription required for memory through the CREB coactivator CRTC1.Increase in synaptic vesicle proteins accompanies long-term potentiation in the dentate gyrus.Regulation of neurotransmitter enzyme by quisqualate subtype glutamate receptors in cultured cerebellar and hippocampal neurons.Extracellular acidification modifies Ca2+ fluxes in rat brain synaptosomes.Different routes of Ca2+ influx in NMDA-mediated generation of nitric oxide and arachidonic acid.Histamine increases ornithine decarboxylase activity in primary cultures of cerebellar granule cells.Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer's diseaseEffect of histamine on the development of astroglial cells in culture
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José Rodríguez-Alvarez
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