Extensive phosphorothioate substitution yields highly active and nuclease-resistant hairpin ribozymes.
about
Dissecting RNA folding by nucleotide analog interference mapping (NAIM)Combinatorial screening and intracellular antiviral activity of hairpin ribozymes directed against hepatitis B virus.Structural basis for heterogeneous kinetics: reengineering the hairpin ribozymeTertiary structure formation in the hairpin ribozyme monitored by fluorescence resonance energy transferSelection of targets and the most efficient hairpin ribozymes for inactivation of mRNAs using a self-cleaving RNA library.Ligation activity of fragmented ribozymes in frozen solution: implications for the RNA world.Identification of phosphate oxygens that are important for self-cleavage activity of the HDV ribozyme by phosphorothioate substitution interference analysis.Analysis of the functional role of a G.A sheared base pair by in vitro genetics.Essential nucleotide sequences and secondary structure elements of the hairpin ribozyme.RNA double cleavage by a hairpin-derived twin ribozyme.Single substitutions of phosphorothioates in the HDV ribozyme G73 define regions necessary for optimal self-cleaving activity.Enzymatic synthesis of 2'-modified nucleic acids: identification of important phosphate and ribose moieties in RNase P substrates.Modification interference approach to detect ribose moieties important for the optimal activity of a ribozyme.A circular trans-acting hepatitis delta virus ribozyme.Specific metal-ion binding sites in a model of the P4-P6 triple-helical domain of a group I intron.
P2860
Q24610481-BF187E4B-14A3-4D01-8C10-D3EDD70AEE5AQ28199404-C365BA28-2C0E-47E8-802E-AC3703F47F18Q28271827-EE711DB8-099C-4496-AEFB-4F6EF61A72D6Q28769589-DBEF4AFF-92D4-4240-BEE1-99D10D536AC6Q31032521-3BFA3DED-3498-4A55-8C6F-A5A122A5FDC4Q34333808-0EE50964-B6FB-4367-88C9-6ED9543C450FQ34873539-52DB7895-82FA-4A40-B98F-0F6655277D0CQ38310336-8C58836A-A36A-4D35-BB9B-8E668174D66EQ38318586-65782F7A-74B2-40D2-9337-F36237E37C42Q39542351-B106AAF5-E3C2-4E5E-8452-DB26A5AB6392Q39722047-99F3E14E-BA72-47F2-BDE6-3B5B8B823DD9Q40394194-974D2B5D-78F1-4477-974A-B41557B399F2Q40404532-711FF5B0-C4AB-423E-B4AC-653361E15096Q40409944-5DA092CF-602E-4879-8EA9-81C097A0D913Q43206867-3131202B-CB8E-4FBF-BFC1-A4C1A7D2A066
P2860
Extensive phosphorothioate substitution yields highly active and nuclease-resistant hairpin ribozymes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Extensive phosphorothioate sub ...... e-resistant hairpin ribozymes.
@en
type
label
Extensive phosphorothioate sub ...... e-resistant hairpin ribozymes.
@en
prefLabel
Extensive phosphorothioate sub ...... e-resistant hairpin ribozymes.
@en
P2860
P356
P1476
Extensive phosphorothioate sub ...... e-resistant hairpin ribozymes.
@en
P2093
P2860
P304
P356
10.1093/NAR/20.11.2835
P577
1992-06-01T00:00:00Z