Topoisomerase I has a strong binding preference for a conserved hexadecameric sequence in the promoter region of the rRNA gene from Tetrahymena pyriformis.
about
Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistantThe domain organization of human topoisomerase IExploring the cellular activity of camptothecin-triple-helix-forming oligonucleotide conjugates.Rapid microtiter assays for poxvirus topoisomerase, mammalian type IB topoisomerase and HIV-1 integrase: application to inhibitor isolationComplete mitochondrial genome sequence of three Tetrahymena species reveals mutation hot spots and accelerated nonsynonymous substitutions in Ymf genesSequence specificity of DNA topoisomerase I in the presence and absence of camptothecin.Dynamic epigenetic control of highly conserved noncoding elements.Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.Efficient homologous and illegitimate recombination in the opportunistic yeast pathogen Candida glabrata.Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant.Structural basis for topoisomerase I inhibition by nucleoside analogs.Distamycin inhibition of topoisomerase I-DNA interaction: a mechanistic analysis.Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae.Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating moleculesMolecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico.Position- and orientation-specific enhancement of topoisomerase I cleavage complexes by triplex DNA structures.An insight into the active site of a type I DNA topoisomerase from the kinetoplastid protozoan Leishmania donovani.A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons.Determination of the recognition sequence of Mycobacterium smegmatis topoisomerase I on mycobacterial genomic sequences.Sequence specific interaction of Mycobacterium smegmatis topoisomerase I with duplex DNA.Real-time investigation of human topoisomerase I reaction kinetics using an optical sensor: a fast method for drug screening and determination of active enzyme concentrations.DNA contacts stimulate catalysis by a poxvirus topoisomerase.Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional PtII complexes.
P2860
Q28534477-8C2FC059-16B0-42A0-86FF-F5E18331E6A2Q28910330-0E287E02-A4C3-4DDD-9C82-B0A84C2EE42AQ30446938-3999B6F9-AB0C-41B1-BF1A-3D0BABB4A5CCQ30635816-5D19292D-B321-4BB4-9F64-1E43CBBE7EB3Q33291756-2470A101-E865-4127-A957-5C58C35B5BE7Q33929257-59CDD901-B794-43EE-B272-D59B486F185EQ34301719-C37303AE-79D8-451C-90A2-986612B910FFQ34336896-63B39C92-4863-4F24-96C6-C35576ADBA75Q34606524-975A1852-C797-42AD-A16D-43AE3B6B45A8Q34967081-DBBF0169-E692-4362-8FB9-10DC1DB5A28AQ35130480-09EB170E-1708-4791-9868-4F38C117E7ECQ35562431-2DF3C5D9-6E24-4E26-96C5-0FA8DEEC55ADQ35837220-210B8471-3ACA-4B20-804F-666B767BBDC5Q36558770-4950B608-C331-4B26-B590-3EA10A7D2AF4Q36765809-5CFB8212-37A8-4F59-B157-EC7B9AAE593AQ37155139-19FC2F6D-F49D-494D-BBD3-D562FDDD2386Q37564077-517BC990-0771-4877-BDF8-4E0FCE0B7ADCQ38292658-AAD42F24-0735-46C1-A201-2BDBD703EBFDQ38297510-6EC936DF-5B52-4546-A5EA-58430C2E4BB6Q38314027-34898FC0-32C5-4322-8E98-FE08A4F025A2Q38337251-9AB7EE30-498E-4AA8-A726-6C878ACC6F37Q39008246-922272EF-3B41-4C56-B6D5-23E6002AB546Q41616296-821134E8-985E-43A4-8282-680FE7D2DA57Q41857079-D82499BB-F0DE-4020-BA8B-A4EBAE0A261D
P2860
Topoisomerase I has a strong binding preference for a conserved hexadecameric sequence in the promoter region of the rRNA gene from Tetrahymena pyriformis.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
Topoisomerase I has a strong b ...... e from Tetrahymena pyriformis.
@en
type
label
Topoisomerase I has a strong b ...... e from Tetrahymena pyriformis.
@en
prefLabel
Topoisomerase I has a strong b ...... e from Tetrahymena pyriformis.
@en
P2093
P2860
P356
P1476
Topoisomerase I has a strong b ...... e from Tetrahymena pyriformis.
@en
P2093
Andersen AH
Nielsen OF
Westergaard O
P2860
P304
P356
10.1093/NAR/13.5.1543
P577
1985-03-01T00:00:00Z