about
Cellular internalization mechanism and intracellular trafficking of filamentous M13 phages displaying a cell-penetrating transbody and TAT peptideBacterial cell surface display of an enzyme library for selective screening of improved cellulase variantsScreening and characterization of a novel esterase from a metagenomic library.Improved mutants from directed evolution are biased to orthologous substitutions.Construction and characterization of a pseudo-immune human antibody library using yeast surface display.Gene silencing by cell-penetrating, sequence-selective and nucleic-acid hydrolyzing antibodiesEngineering of a human kringle domain into agonistic and antagonistic binding proteins functioning in vitro and in vivo.Antibody targeting intracellular oncogenic Ras mutants exerts anti-tumour effects after systemic administration.A variant of green fluorescent protein exclusively deposited to active intracellular inclusion bodies.Directed evolution to probe protein allostery and integrin I domains of 200,000-fold higher affinity.Construction of a large synthetic human Fab antibody library on yeast cell surface by optimized yeast mating.Humanization of a phosphothreonine peptide-specific chicken antibody by combinatorial library optimization of the phosphoepitope-binding motif.Engineering of Immunoglobulin Fc Heterodimers Using Yeast Surface-Displayed Combinatorial Fc Library ScreeningExtracellular Release of CD11b by TLR9 Stimulation in MacrophagesEffects of sucrose on conformational equilibria and fluctuations within the native-state ensemble of proteinsAn anti-nucleic acid antibody delivers antigen to the cross-presentation pathway in dendritic cells and potentiates therapeutic antitumor effectsAn RNA-hydrolyzing recombinant antibody exhibits an antiviral activity against classical swine fever virus.Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor.Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure.High-pressure studies of aggregation of recombinant human interleukin-1 receptor antagonist: thermodynamics, kinetics, and application to accelerated formulation studies.Temperature adaptation in Gillichthys (Teleost: Gobiidae) A(4)-lactate dehydrogenases: identical primary structures produce subtly different conformations.Kinetics and energetics of assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein. Insights into transition states from pressure, temperature, and co-solute studies.Purification and characterization of two polymorphic variants of short chain acyl-CoA dehydrogenase reveal reduction of catalytic activity and stability of the Gly185Ser enzyme.Optimized stability retention of a monoclonal antibody in the PLGA nanoparticles.Production of recombinant human procollagen type I C-terminal propeptide and establishment of a sandwich ELISA for quantification.Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation.Immunoglobulin Fc-Fused Peptide without C-Terminal Arg or Lys Residue Augments Neuropilin-1-Dependent Tumor Vascular Permeability.Effect of a novel fully human monovalent antigen-binding fragment on the survival of cancer cell lines.A human kringle domain-based fluorescence-linked immunosorbent assay system.Directed evolution of the epidermal growth factor receptor extracellular domain for expression in yeast.High-pressure studies on protein aggregates and amyloid fibrils.Immunoglobulin Fc-fused, neuropilin-1-specific peptide shows efficient tumor tissue penetration and inhibits tumor growth via anti-angiogenesis.Isomaltulose production via yeast surface display of sucrose isomerase from Enterobacter sp. FMB-1 on Saccharomyces cerevisiae.High-level production of Fc-fused kringle domain in Pichia pastoris.High-level production of a kringle domain variant by high-cell-density cultivation of Escherichia coli.HDAC4 degradation by combined TRAIL and valproic acid treatment induces apoptotic cell death of TRAIL-resistant head and neck cancer cellsThermodynamic modulation of light chain amyloid fibril formationHomomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptorsExpression of soluble and functional human neonatal Fc receptor in Pichia pastorisHeterodimeric Fc-fused IL12 shows potent antitumor activity by generating memory CD8+ T cells
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Yong-Sung Kim
@ast
Yong-Sung Kim
@en
Yong-Sung Kim
@es
Yong-Sung Kim
@sl
type
label
Yong-Sung Kim
@ast
Yong-Sung Kim
@en
Yong-Sung Kim
@es
Yong-Sung Kim
@sl
prefLabel
Yong-Sung Kim
@ast
Yong-Sung Kim
@en
Yong-Sung Kim
@es
Yong-Sung Kim
@sl
P106
P108
P2798
P31
P496
0000-0003-2673-1509