De novo design of peptide immunogens that mimic the coiled coil region of human T-cell leukemia virus type-1 glycoprotein 21 transmembrane subunit for induction of native protein reactive neutralizing antibodies.
about
A continuous peptide epitope reacting with pandemic influenza AH1N1 predicted by bioinformatic approaches.Preliminary data on Pemphigus vulgaris treatment by a proteomics-defined peptide: a case report.Structure of a proteolytically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion proteinPeptide-based antibodies against glutathione-binding domains suppress superoxide production mediated by mitochondrial complex I.Covalent stabilization of coiled coils of the HIV gp41 N region yields extremely potent and broad inhibitors of viral infection.Design and use of peptide-based antibodies decreasing superoxide production by mitochondrial complex I and complex II.Engineered conformation-dependent VEGF peptide mimics are effective in inhibiting VEGF signaling pathways.Combination treatment with HER-2 and VEGF peptide mimics induces potent anti-tumor and anti-angiogenic responses in vitro and in vivoImmunization with synthetic VEGF peptides in ovarian cancerMolecular determinants of human T-lymphotropic virus type 1 transmission and spread.Animal models for human T-lymphotropic virus type 1 (HTLV-1) infection and transformation.Immunotherapy with HER-2 and VEGF peptide mimics plus metronomic paclitaxel causes superior antineoplastic effects in transplantable and transgenic mouse models of human breast cancerCombined vaccination with HER-2 peptide followed by therapy with VEGF peptide mimics exerts effective anti-tumor and anti-angiogenic effects in vitro and in vivo.Protein tyrosine nitration of the flavin subunit is associated with oxidative modification of mitochondrial complex II in the post-ischemic myocardium.Protein engineering strategies for the development of viral vaccines and immunotherapeutics.Immunization with a novel chimeric peptide representing B and T cell epitopes from HER2 extracellular domain (HER2 ECD) for breast cancer.Profiling pancreatic cancer-secreted proteome using 15N amino acids and serum-free media.Conformational HER-2/neu B-cell epitope peptide vaccine designed to incorporate two native disulfide bonds enhances tumor cell binding and antitumor activities.Recombinant HBHA boosting effect on BCG-induced immunity against Mycobacterium tuberculosis infection.Design of affinity peptides from natural protein ligands: A study of the cardiac troponin complex.General and Facile Route to Isomerically Pure Tricyclic Peptides Based on Templated Tandem CLIPS/CuAAC Cyclizations.Resistance to neutralization by antibodies targeting the coiled coil of fusion-active envelope is a common feature of retroviruses.
P2860
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P2860
De novo design of peptide immunogens that mimic the coiled coil region of human T-cell leukemia virus type-1 glycoprotein 21 transmembrane subunit for induction of native protein reactive neutralizing antibodies.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
De novo design of peptide immu ...... ctive neutralizing antibodies.
@en
type
label
De novo design of peptide immu ...... ctive neutralizing antibodies.
@en
prefLabel
De novo design of peptide immu ...... ctive neutralizing antibodies.
@en
P2093
P2860
P921
P356
P1476
De novo design of peptide immu ...... ctive neutralizing antibodies.
@en
P2093
Marcus P Lynch
Pravin T P Kaumaya
Roshni Sundaram
Sharad V Rawale
Yiping Sun
P2860
P304
24141-24151
P356
10.1074/JBC.M313210200
P407
P577
2004-04-01T00:00:00Z