Degadration of mismatch repair hMutSalpha heterodimer by the ubiquitin-proteasome pathway.
about
Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cellsStructural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activitiesMSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice.Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humansHDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα.Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair.Fusion tyrosine kinase NPM-ALK Deregulates MSH2 and suppresses DNA mismatch repair function novel insights into a potent oncoproteinProteasome inhibition rescues clinically significant unstable variants of the mismatch repair protein Msh2.The ubiquitin-proteasome system in cancer, a major player in DNA repair. Part 1: post-translational regulation.HuCOP1 contributes to the regulation of DNA repair in keratinocytes.NPM-ALK mediates phosphorylation of MSH2 at tyrosine 238, creating a functional deficiency in MSH2 and the loss of mismatch repair.A quest for human and mouse embryonic stem cell-specific proteins.Proteome Stability as a Key Factor of Genome Integrity.
P2860
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P2860
Degadration of mismatch repair hMutSalpha heterodimer by the ubiquitin-proteasome pathway.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Degadration of mismatch repair ...... ubiquitin-proteasome pathway.
@en
type
label
Degadration of mismatch repair ...... ubiquitin-proteasome pathway.
@en
prefLabel
Degadration of mismatch repair ...... ubiquitin-proteasome pathway.
@en
P2093
P2860
P1433
P1476
Degadration of mismatch repair ...... ubiquitin-proteasome pathway.
@en
P2093
Bernard Salles
Dominique Lautier
Guy Laurent
Hélène Hernandez-Pigeon
Odile Humbert
P2860
P356
10.1016/S0014-5793(04)00181-4
P407
P577
2004-03-01T00:00:00Z