Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinofuranosylcytosine in leukemia and solid tumor cell lines.
about
A phase I-II study of elacytarabine (CP-4055) in the treatment of patients with ovarian cancer resistant or refractory to platinum therapy.Elacytarabine has single-agent activity in patients with advanced acute myeloid leukaemiaCellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles.Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.Development of cytarabine prodrugs and delivery systems for leukemia treatment.Elacytarabine--lipid vector technology overcoming drug resistance in acute myeloid leukemia.Lipophilic prodrugs and formulations of conventional (deoxy)nucleoside and fluoropyrimidine analogs in cancer.Late-phase investigational approaches for the treatment of relapsed/refractory acute myeloid leukemia.Elacytarabine: lipid vector technology under investigation in acute myeloid leukemia.Novel therapeutics in acute myeloid leukemia.Clinical potential of elacytarabine in patients with acute myeloid leukemia.Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126Induction of resistance to the lipophilic cytarabine prodrug elacytarabine (CP-4055) in CEM leukemic cells.Troxacitabine prodrugs for pancreatic cancer.Development and characterization of a long-acting nanoformulated abacavir prodrugA novel biocatalytic approach to acetylation of 1-β-D-arabinofuranosylcytosine by Aspergillus oryzae whole cell in organic solvents.Oral 4-(N)-stearoyl gemcitabine nanoparticles inhibit tumor growth in mouse models.Intravenous administration of CP-4055 (ELACYT) in patients with solid tumours. A Phase I study.Nucleoside and nucleobase analogs in cancer treatment: not only sapacitabine, but also gemcitabine.
P2860
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P2860
Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinofuranosylcytosine in leukemia and solid tumor cell lines.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Antiproliferative activity and ...... ia and solid tumor cell lines.
@en
type
label
Antiproliferative activity and ...... ia and solid tumor cell lines.
@en
prefLabel
Antiproliferative activity and ...... ia and solid tumor cell lines.
@en
P2093
P1476
Antiproliferative activity and ...... ia and solid tumor cell lines.
@en
P2093
Bergman AM
Hendriks HR
Sandvold ML
P304
P356
10.1016/J.BCP.2003.09.028
P407
P577
2004-02-01T00:00:00Z