Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells. - Wikidata - awgldk - TriplyDB

Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells.

Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells.

http://www.wikidata.org/entity/Q40576914

about

Human glioma growth is controlled by microRNA-10b Bioactive lipids and the control of Bax pro-apoptotic activity Novel chemo-sensitizing agent, ERW1227B, impairs cellular motility and enhances cell death in glioblastomas Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells.Statins and neuroprotection: a prescription to move the field forward Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma.BCL2 family of apoptosis-related genes: functions and clinical implications in cancer.Use of statins and risk of glioma: a nationwide case-control study in Denmark Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.Statins, Bcl-2, and apoptosis: cell death or cell protection?Statins are Associated With a Reduced Risk of Brain Cancer: A Population-Based Case-Control Study.Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.Simvastatin inhibits protein isoprenylation in the brain.The interplay between cell signalling and the mevalonate pathway in cancer.Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells.Determination of Cell Death Induced by Lovastatin on Human Colon Cell Line HT29 Using the Comet Assay.Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells.Cytotoxic effects of statins and thiazolidinediones on meningioma cells.Lovastatin enhances gefitinib activity in glioblastoma cells irrespective of EGFRvIII and PTEN status.Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis.Identification of a specific domain responsible for JNK2alpha2 autophosphorylation.Mitochondrial outer membrane permeabilization: a focus on the role of mitochondrial membrane structural organization.Targeting proliferating tumor cells via the transcriptional control of therapeutic genes.

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P2860

Lovastatin-induced up-regulation of the BH3-only protein, Bim, and cell death in glioblastoma cells.

http://www.wikidata.org/entity/Q40576914

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

Lovastatin-induced up-regulati ...... l death in glioblastoma cells.

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type

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Lovastatin-induced up-regulati ...... l death in glioblastoma cells.

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Lovastatin-induced up-regulati ...... l death in glioblastoma cells.

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J.1471-4159.2004.02319.X

P1433

Journal of Neurochemistry

P1476

Lovastatin-induced up-regulati ...... l death in glioblastoma cells.

@en

P2093

Keith M Rich

http://www.w3.org/2001/XMLSchema#string

Richard A Lytle

http://www.w3.org/2001/XMLSchema#string

Ryuji Higashikubo

http://www.w3.org/2001/XMLSchema#string

Xiao Zheng

http://www.w3.org/2001/XMLSchema#string

Zhihong Jiang

http://www.w3.org/2001/XMLSchema#string

P2860

Bim: a novel member of the Bcl-2 family that promotes apoptosis

Rho GTPases and the actin cytoskeleton

BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins.

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

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168-178

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10.1111/J.1471-4159.2004.02319.X

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1

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15030401

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