Roscovitine, a cyclin-dependent kinase inhibitor, prevents replication of varicella-zoster virus.
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Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factorsA uniform procedure for the purification of CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1Antiviral activity of CYC202 in HIV-1-infected cellsIdentification and structural-functional analysis of cyclin-dependent kinases of the cattle tick Rhipicephalus (Boophilus) microplusEpizootic hemorrhagic disease virus induces and benefits from cell stress, autophagy, and apoptosis.Establishment of a cell-based assay for screening of compounds inhibiting very early events in the cytomegalovirus replication cycle and characterization of a compound identified using the assay.Targeted therapy for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus.Cholesterol dependence of varicella-zoster virion entry into target cellsIdentification of a varicella-zoster virus replication inhibitor that blocks capsid assembly by interacting with the floor domain of the major capsid protein.Generation of a reporter cell line for detection of infectious varicella-zoster virus and its application to antiviral studies.Delayed biosynthesis of varicella-zoster virus glycoprotein C: upregulation by hexamethylene bisacetamide and retinoic acid treatment of infected cells.Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle.Ser-634 and Ser-636 of Kaposi's Sarcoma-Associated Herpesvirus RTA are Involved in Transactivation and are Potential Cdk9 Phosphorylation Sites.Cdk inhibitory nucleoside analogs prevent transcription from viral genomes.Varicella-zoster virus modulates NF-kappaB recruitment on selected cellular promotersVaricella-zoster virus ORF12 protein activates the phosphatidylinositol 3-kinase/Akt pathway to regulate cell cycle progression.Five years of progress on cyclin-dependent kinases and other cellular proteins as potential targets for antiviral drugs.Regulation of the retinoblastoma proteins by the human herpesviruses.Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction.Functions of the C-terminal domain of varicella-zoster virus glycoprotein E in viral replication in vitro and skin and T-cell tropism in vivo.Potential of protein kinase inhibitors for treating herpesvirus-associated disease.β-l-1-[5-(E-2-bromovinyl)-2-(hydroxymethyl)-1,3-(dioxolan-4-yl)] uracil (l-BHDU) prevents varicella-zoster virus replication in a SCID-Hu mouse model and does not interfere with 5-fluorouracil catabolism.Analysis of viral and cellular factors influencing herpesvirus-induced nuclear envelope breakdownVaricella-zoster virus infection of human fibroblast cells activates the c-Jun N-terminal kinase pathway.Cyclin-dependent kinase activity is required for efficient expression and posttranslational modification of human cytomegalovirus proteins and for production of extracellular particles.Varicella-zoster virus infection of human foreskin fibroblast cells results in atypical cyclin expression and cyclin-dependent kinase activity.Varicella-zoster virus IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity.Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu miceCyclin-dependent kinase 1/cyclin B1 phosphorylates varicella-zoster virus IE62 and is incorporated into virions.Inhibition of the cyclin-dependent kinases at the beginning of human cytomegalovirus infection specifically alters the levels and localization of the RNA polymerase II carboxyl-terminal domain kinases cdk9 and cdk7 at the viral transcriptosome.Replication of varicella-zoster virus in human skin organ culture
P2860
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P2860
Roscovitine, a cyclin-dependent kinase inhibitor, prevents replication of varicella-zoster virus.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Roscovitine, a cyclin-dependen ...... ion of varicella-zoster virus.
@en
type
label
Roscovitine, a cyclin-dependen ...... ion of varicella-zoster virus.
@en
prefLabel
Roscovitine, a cyclin-dependen ...... ion of varicella-zoster virus.
@en
P2093
P2860
P1433
P1476
Roscovitine, a cyclin-dependen ...... ion of varicella-zoster virus.
@en
P2093
Andrew Brooks
Jennifer F Moffat
Paul R Kinchington
Shannon L Taylor
P2860
P304
P356
10.1128/JVI.78.6.2853-2862.2004
P407
P577
2004-03-01T00:00:00Z