Constitutive and induced CD44 shedding by ADAM-like proteases and membrane-type 1 matrix metalloproteinase.
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The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.Pancreatic cancer stem cell markers and exosomes - the incentive pushCD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating CellsCharacterization of CD200 Ectodomain SheddingThe intracellular domain of CD44 promotes the fusion of macrophagesMatrix metalloproteinases, T cell homing and beta-cell mass in type 1 diabetes.Soluble CD44 interacts with intermediate filament protein vimentin on endothelial cell surface.ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1).Increased expression of surface CD44 in hypoxia-DCs skews helper T cells toward a Th2 polarization.CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2.ADAM proteases, ErbB pathways and cancer.The liberation of CD44 intracellular domain modulates adenoviral vector transgene expression.MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells.MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells.TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent.Ectodomain Shedding of Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE-1) Is Induced by Vascular Endothelial Growth Factor A (VEGF-A)Membrane type 1-matrix metalloproteinase: substrate diversity in pericellular proteolysis.MicroRNA-655-3p functions as a tumor suppressor by regulating ADAM10 and β-catenin pathway in Hepatocellular Carcinoma.Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.Intracellular domain fragment of CD44 alters CD44 function in chondrocytes.Mesenchymal CD44 expression contributes to the acquisition of an activated fibroblast phenotype via TWIST activation in the tumor microenvironmentIdentification and characterization of Lutheran blood group glycoprotein as a new substrate of membrane-type 1 matrix metalloproteinase 1 (MT1-MMP): a systemic whole cell analysis of MT1-MMP-associating proteins in A431 cells.Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancyMonitoring and Inhibiting MT1-MMP during Cancer Initiation and Progression.CD44 integrates signaling in normal stem cell, cancer stem cell and (pre)metastatic niches.Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling.Matrix metalloproteinases in the brain and blood-brain barrier: Versatile breakers and makers.Phorbol ester-induced shedding of the prostate cancer marker transmembrane protein with epidermal growth factor and two follistatin motifs 2 is mediated by the disintegrin and metalloproteinase-17.Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-kDa extracellular matrix metalloproteinase inducer (EMMPRIN) fragment from tumor cells.Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells.Mechanism of metastasis by membrane type 1-matrix metalloproteinase in hepatocellular carcinoma.A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44The protein kinase C cascade regulates recruitment of matrix metalloprotease 9 to podosomes and its release and activation.Membrane localization of membrane type 1 matrix metalloproteinase by CD44 regulates the activation of pro-matrix metalloproteinase 9 in osteoclasts.Induction of CD44 cleavage in articular chondrocytes.MT1-MMP and RECK are involved in human CD34+ progenitor cell retention, egress, and mobilization.Inhibition of membrane type-1 matrix metalloproteinase by cancer drugs interferes with the homing of diabetogenic T cells into the pancreas.Non-proteolytic, receptor/ligand interactions associate cellular membrane type-1 matrix metalloproteinase with the complement component C1q.Collagens, stromal cell-derived factor-1alpha and basic fibroblast growth factor increase cancer cell invasiveness in a hyaluronan hydrogel.Soluble CD44 concentration in the serum and peritoneal fluid samples of patients with different stages of endometriosis.
P2860
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P2860
Constitutive and induced CD44 shedding by ADAM-like proteases and membrane-type 1 matrix metalloproteinase.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Constitutive and induced CD44 ...... pe 1 matrix metalloproteinase.
@en
type
label
Constitutive and induced CD44 ...... pe 1 matrix metalloproteinase.
@en
prefLabel
Constitutive and induced CD44 ...... pe 1 matrix metalloproteinase.
@en
P2093
P1433
P1476
Constitutive and induced CD44 ...... ype 1 matrix metalloproteinase
@en
P2093
Hirokazu Matsuki
Kaori Taniwaki
Kayoko Yonezawa
Masato Fujii
Motoharu Seiki
Naoko Suenaga
P304
P356
10.1158/0008-5472.CAN-03-3502
P407
P577
2004-02-01T00:00:00Z