Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
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Toward a modern synthesis of immunity: Charles A. Janeway Jr. and the immunologist's dirty little secretPathogen recognition and inflammatory signaling in innate immune defensesSystems biology applied to vaccine and immunotherapy developmentImmune response to vaccine adjuvants during the first year of lifeAge-dependent maturation of Toll-like receptor-mediated cytokine responses in Gambian infantsIn situ photoimmunotherapy: a tumour-directed treatment for melanoma.Immunogenomics and systems biology of vaccines.Both innate immunity and type 1 humoral immunity to Streptococcus pneumoniae are mediated by MyD88 but differ in their relative levels of dependence on toll-like receptor 2.Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis.Systemic stimulation of TLR2 impairs neonatal mouse brain development.Development of newborn and infant vaccinesProduction of inflammatory cytokines in response to diphtheria-pertussis-tetanus (DPT), haemophilus influenzae type b (Hib), and 7-valent pneumococcal (PCV7) vaccines.Haemophilus influenzae type b conjugate vaccines.Immunization of aged mice with a pneumococcal conjugate vaccine combined with an unmethylated CpG-containing oligodeoxynucleotide restores defective immunoglobulin G antipolysaccharide responses and specific CD4+-T-cell priming to young adult levelsAntibody response specific to the capsular polysaccharide is impaired in Streptococcus suis serotype 2-infected animals.Vibrio cholerae porin OmpU induces pro-inflammatory responses, but down-regulates LPS-mediated effects in RAW 264.7, THP-1 and human PBMCs.Outer membrane protein complex of Meningococcus enhances the antipolysaccharide antibody response to pneumococcal polysaccharide-CRM₁₉₇ conjugate vaccine.Sustained high-titer antibody responses induced by conjugating a malarial vaccine candidate to outer-membrane protein complex.Toll-like receptors in the pathogenesis of human disease.TLR9 -1486T/C and 2848C/T SNPs Are Associated with Human Cytomegalovirus Infection in InfantsA bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2.Agonists of Toll-like receptors 3, 4, 7, and 9 are candidates for use as adjuvants in an outer membrane vaccine against Neisseria meningitidis serogroup B.Sporozoite neutralizing antibodies elicited in mice and rhesus macaques immunized with a Plasmodium falciparum repeat peptide conjugated to meningococcal outer membrane protein complexToll or toll-free adjuvant path toward the optimal vaccine development.Neisseria meningitidis PorB, a Toll-like receptor 2 ligand, improves the capacity of Francisella tularensis lipopolysaccharide to protect mice against experimental tularemia.An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions.Enhanced antibody responses to a detoxified lipopolysaccharide-group B meningococcal outer membrane protein vaccine are due to synergistic engagement of Toll-like receptorsAdjuvant-induced Human Monocyte Secretome Profiles Reveal Adjuvant- and Age-specific Protein Signatures.Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides.B-cell responses to vaccination at the extremes of age.Developmental biology of the innate immune response: implications for neonatal and infant vaccine development.Drugs targeting Toll-like receptors.Toll-like receptor 2-dependent protection against pneumococcal carriage by immunization with lipidated pneumococcal proteins.Novel regulatory functions for Toll-like receptor-activated B cells during intracellular bacterial infection.Mechanisms underlying in vivo polysaccharide-specific immunoglobulin responses to intact extracellular bacteria.Toll-like receptors in neonatal sepsis.The history of pneumococcal conjugate vaccine development: dose selection.Staphylococcus aureus lipoproteins trigger human corneal epithelial innate response through toll-like receptor-2Distinct Mechanisms Underlie Boosted Polysaccharide-Specific IgG Responses Following Secondary Challenge with Intact Gram-Negative versus Gram-Positive Extracellular Bacteria.Anti-tumor activity of Acinetobacter baumannii outer membrane protein A on dendritic cell-based immunotherapy against murine melanoma.
P2860
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P2860
Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Haemophilus influenzae type b- ...... R2 for optimal immunogenicity.
@en
type
label
Haemophilus influenzae type b- ...... R2 for optimal immunogenicity.
@en
prefLabel
Haemophilus influenzae type b- ...... R2 for optimal immunogenicity.
@en
P2093
P1476
Haemophilus influenzae type b- ...... R2 for optimal immunogenicity.
@en
P2093
Douglas T Golenbock
Eicke Latz
Jennifer Franko
John R Schreiber
P304
P356
10.4049/JIMMUNOL.172.4.2431
P407
P577
2004-02-01T00:00:00Z