Protecting genome integrity during CRISPR immune adaptation.
about
Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity.Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.Casposons: mobile genetic elements that gave rise to the CRISPR-Cas adaptation machinery.CRISPR-Cas: Adapting to change.Structures of the CRISPR genome integration complex.Conserved DNA motifs in the type II-A CRISPR leader region.Asymmetric positioning of Cas1-2 complex and Integration Host Factor induced DNA bending guide the unidirectional homing of protospacer in CRISPR-Cas type I-E system.The CRISPR Spacer Space Is Dominated by Sequences from Species-Specific Mobilomes.Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.Prespacer processing and specific integration in a Type I-A CRISPR system.Spontaneous CRISPR loci generation in vivo by non-canonical spacer integration.How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays.Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.Molecular organization of the type II-A CRISPR adaptation module and its interaction with Cas9 via Csn2
P2860
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P2860
Protecting genome integrity during CRISPR immune adaptation.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Protecting genome integrity during CRISPR immune adaptation.
@en
type
label
Protecting genome integrity during CRISPR immune adaptation.
@en
prefLabel
Protecting genome integrity during CRISPR immune adaptation.
@en
P2860
P356
P1476
Protecting genome integrity during CRISPR immune adaptation.
@en
P2093
Addison V Wright
P2860
P2888
P304
P356
10.1038/NSMB.3289
P577
2016-09-05T00:00:00Z