The voltage-dependent ClC-2 chloride channel has a dual gating mechanism.
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A guide to Ussing chamber studies of mouse intestineRemoval of gating in voltage-dependent ClC-2 chloride channel by point mutations affecting the pore and C-terminus CBS-2 domainConformational changes required for H+/Cl− exchange mediated by a CLC transporterAssociation between Hsp90 and the ClC-2 chloride channel upregulates channel functionFunctional evaluation of human ClC-2 chloride channel mutations associated with idiopathic generalized epilepsiesResearch and progress on ClC‑2 (Review).GlialCAM, a CLC-2 Cl(-) channel subunit, activates the slow gate of CLC chloride channels.CLC channel function and dysfunction in health and disease.Physiology and pathophysiology of ClC-K/barttin channels.Toward a unifying model of malaria-induced channel activity.Tryptophan Scanning Mutagenesis Identifies the Molecular Determinants of Distinct Barttin Functions.GCK-3, a newly identified Ste20 kinase, binds to and regulates the activity of a cell cycle-dependent ClC anion channelClC chloride channels viewed through a transporter lens.Quantitative analysis of the voltage-dependent gating of mouse parotid ClC-2 chloride channel.Regulatory phosphorylation induces extracellular conformational changes in a CLC anion channelRelative contribution of chloride channels and transporters to regulatory volume decrease in human glioma cellsCLC-0 and CFTR: chloride channels evolved from transporters.Chloride channelopathies of ClC-2.Cell biology and physiology of CLC chloride channels and transporters.Structure and gating of CLC channels and exchangers.Methadone but not morphine inhibits lubiprostone-stimulated Cl- currents in T84 intestinal cells and recombinant human ClC-2, but not CFTR Cl- currents.Lubiprostone activates Cl- secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84.Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval.Voltage-dependent and -independent titration of specific residues accounts for complex gating of a ClC chloride channel by extracellular protons.Gating of human ClC-2 chloride channels and regulation by carboxy-terminal domains.Membrane cholesterol content modulates ClC-2 gating and sensitivity to oxidative stress.A synthetic prostone activates apical chloride channels in A6 epithelial cells.Regulation of ClC-2 gating by intracellular ATP.Anion- and proton-dependent gating of ClC-4 anion/proton transporter under uncoupling conditions.Altered gating and regulation of a carboxy-terminal ClC channel mutant expressed in the Caenorhabditis elegans oocyte.Residues important for nitrate/proton coupling in plant and mammalian CLC transporters.Single myotonia mutation strikes multiple mechanisms of a chloride channel.Leukoencephalopathy-causing CLCN2 mutations are associated with impaired Cl- channel function and trafficking.CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and PhysiologyMolecular determinants of common gating of a ClC chloride channel
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P2860
The voltage-dependent ClC-2 chloride channel has a dual gating mechanism.
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2004 nî lūn-bûn
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2004年の論文
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2004年論文
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2004年論文
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2004年論文
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2004年論文
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name
The voltage-dependent ClC-2 chloride channel has a dual gating mechanism.
@en
type
label
The voltage-dependent ClC-2 chloride channel has a dual gating mechanism.
@en
prefLabel
The voltage-dependent ClC-2 chloride channel has a dual gating mechanism.
@en
P2093
P2860
P1476
The voltage-dependent ClC-2 chloride channel has a dual gating mechanism.
@en
P2093
Diego Varela
Francisco V Sepúlveda
L Pablo Cid
Leandro Zúñiga
Marcelo Catalán
María Isabel Niemeyer
P2860
P304
P356
10.1113/JPHYSIOL.2003.060046
P407
P577
2004-01-14T00:00:00Z