A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung cancer
about
Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas.Phase I trial of the oral smoothened inhibitor sonidegib in combination with paclitaxel in patients with advanced solid tumors.Hedgehog inhibitor sonidegib potentiates 177Lu-octreotate therapy of GOT1 human small intestine neuroendocrine tumors in nude miceThe clinical utility of circulating tumour cells in patients with small cell lung cancer.Membrane-bound full-length Sonic Hedgehog identifies cancer stem cells in human non-small cell lung cancer.Strategies to target the Hedgehog signaling pathway for cancer therapy.Microvesicles releasing by oral cancer cells enhance endothelial cell angiogenesis via Shh/RhoA signaling pathway.Old Sonic Hedgehog, new tricks: a new paradigm in thoracic malignancies.Transcriptional deregulation underlying the pathogenesis of small cell lung cancer.Hedgehog Signaling in Lung Cancer: From Oncogenesis to Cancer Treatment ResistanceHedgehog Signaling Pathway and Autophagy in Cancer
P2860
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P2860
A phase I trial of the Hedgehog inhibitor, sonidegib (LDE225), in combination with etoposide and cisplatin for the initial treatment of extensive stage small cell lung cancer
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
A phase I trial of the Hedgeho ...... e stage small cell lung cancer
@en
type
label
A phase I trial of the Hedgeho ...... e stage small cell lung cancer
@en
prefLabel
A phase I trial of the Hedgeho ...... e stage small cell lung cancer
@en
P2093
P2860
P1433
P1476
A phase I trial of the Hedgeho ...... e stage small cell lung cancer
@en
P2093
Andrei I Holodny
Anna M Varghese
Anya M Litvak
Cami S Sima
Helen H Won
Jerrold B Teitcher
Kaitlin M Woo
Kenneth K Ng
Lee M Krug
M Catherine Pietanza
P2860
P356
10.1016/J.LUNGCAN.2016.04.014
P577
2016-04-26T00:00:00Z