Episodic evolution of pyrin in primates: human mutations recapitulate ancestral amino acid states.
about
Structural and functional insights into the B30.2/SPRY domain.Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)Update on Pyrin Functions and Mechanisms of Familial Mediterranean FeverInteraction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosisReconstructing large regions of an ancestral mammalian genome in silicoRelating the disease mutation spectrum to the evolution of the cystic fibrosis transmembrane conductance regulator (CFTR)From PPROM to caul: The evolution of membrane rupture in mammals.Structural, expression, and evolutionary analysis of mouse CIAS1Evidence for positive selection in the C-terminal domain of the cholesterol metabolism gene PCSK9 based on phylogenetic analysis in 14 primate speciesEstimating the rate of irreversibility in protein evolution.Accumulating Dobzhansky-Muller incompatibilities: reconciling theory and data.Increased frequency of Mediterranean fever gene variants in multiple myeloma.Dobzhansky-Muller incompatibilities in protein evolution.Human endogenous retroviral elements as indicators of ectopic recombination events in the primate genome.Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy.Genetics of population isolates.Applications of selective neutrality tests to molecular ecology.Inflammasomes and their activation.Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice.High Frequency of Inherited Variants in the MEFV Gene in Acute Lymphocytic Leukemia.Identification of a genomic reservoir for new TRIM genes in primate genomes.Crystal structure of TRIM20 C-terminal coiled-coil/B30.2 fragment: implications for the recognition of higher order oligomersHuman genomic disease variants: a neutral evolutionary explanation.CATERPILLERs, pyrin and hereditary immunological disorders.Management of familial Mediterranean fever by colchicine does not normalize the altered profile of microbial long chain fatty acids in the human metabolome.Clinical features and functional significance of the P369S/R408Q variant in pyrin, the familial Mediterranean fever protein.The control of viral infection by tripartite motif proteins and cyclophilin A.Developments in the scientific and clinical understanding of autoinflammatory disordersEvolution and comparative genomics of odorant- and pheromone-associated genes in rodents.Comparative evolutionary genomics of androgen-binding protein genes.Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation.Monogenic Autoinflammatory Diseases with Mendelian Inheritance: Genes, Mutations, and Genotype/Phenotype Correlations.High frequency of inherited variants in the MEFV gene in patients with hematologic neoplasms: a genetic susceptibility?Differential Expression of miR-4520a Associated With Pyrin Mutations in Familial Mediterranean Fever (FMF).Geoepidemiology and Immunologic Features of Autoinflammatory Diseases: a Comprehensive Review.Y chromosome palindromes and gene conversion.Pyrin and ASC co-localize to cellular sites that are rich in polymerizing actin.Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing.A population genetics study of the familial Mediterranean fever gene: evidence of balancing selection under an overdominance regime.
P2860
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P2860
Episodic evolution of pyrin in primates: human mutations recapitulate ancestral amino acid states.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Episodic evolution of pyrin in ...... e ancestral amino acid states.
@en
type
label
Episodic evolution of pyrin in ...... e ancestral amino acid states.
@en
prefLabel
Episodic evolution of pyrin in ...... e ancestral amino acid states.
@en
P2093
P356
P1433
P1476
Episodic evolution of pyrin in ...... e ancestral amino acid states.
@en
P2093
I Aksentijevich
N Richards
P2888
P304
P356
10.1038/85893
P407
P577
2001-03-01T00:00:00Z
P6179
1022763699