Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
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Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinomaFragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancerWWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcomeCorrelated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with carcinogenesis.A novel approach to simultaneously scan genes at fragile sitesWWOX hypomorphic mice display a higher incidence of B-cell lymphomas and develop testicular atrophy.WWOX protein expression in normal human tissues.Frequent loss of WWOX expression in breast cancer: correlation with estrogen receptor statusWWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear.Molecular analysis of WWOX expression correlation with proliferation and apoptosis in glioblastoma multiformeDrosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species.Fhit delocalizes annexin a4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel.WWOX suppresses prostate cancer cell progression through cyclin D1-mediated cell cycle arrest in the G1 phase.Expression of WW domain-containing oxidoreductase WWOX in pterygiumThe JNK inhibitor SP600129 enhances apoptosis of HCC cells induced by the tumor suppressor WWOX.Reduced expression of the WW domain-containing oxidoreductase in human hematopoietic malignancies.Alteration of WWOX in human cancer: a clinical view.WWOX: a fragile tumor suppressor.WWOX, large common fragile site genes, and cancer.Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors.WWOX induces apoptosis and inhibits proliferation of human hepatoma cell line SMMC-7721.The Fhit protein: an opportunity to overcome chemoresistance.Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.Recurrent alterations of the WW domain containing oxidoreductase gene spanning the common fragile site FRA16D in multiple myeloma and monoclonal gammopathy of undetermined significance.Characterization of the tumor suppressor gene WWOX in primary human oral squamous cell carcinomas.Genome wide DNA-profiling of HIV-related B-cell lymphomas.Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events.
P2860
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P2860
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
@en
type
label
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
@en
prefLabel
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
@en
P2093
P1476
Expression of FRA16D/WWOX and FRA3B/FHIT genes in hematopoietic malignancies.
@en
P2093
Andrea Vecchione
Francesco Trapasso
Hideshi Ishii
Kay Huebner
Keiya Ozawa
Krittaya Sutheesophon
Miki Nishimura
Shuang-Yin Han
Tamotsu Kuroki
Teresa Druck
P304
P577
2003-11-01T00:00:00Z