A conserved signal-responsive sequence mediates activation-induced alternative splicing of CD45.
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Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicingSplicing regulation: from a parts list of regulatory elements to an integrated splicing codeThe intranuclear localization and function of YT521-B is regulated by tyrosine phosphorylationExon silencing by UAGG motifs in response to neuronal excitationAlternative splicing of MALT1 controls signalling and activation of CD4(+) T cellsCrystal structures and RNA-binding properties of the RNA recognition motifs of heterogeneous nuclear ribonucleoprotein L: insights into its roles in alternative splicing regulation.Use of transcriptional synergy to augment sensitivity of a splicing reporter assayContext-dependent regulatory mechanism of the splicing factor hnRNP L.The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA.HnRNP L represses exon splicing via a regulated exonic splicing silencer.Differential requirement for the CD45 splicing regulator hnRNPLL for accumulation of NKT and conventional T cellsIn vivo selection reveals combinatorial controls that define a critical exon in the spinal muscular atrophy genes.Cell signalling and the control of pre-mRNA splicing.Regulation of alternative splicing by reversible protein phosphorylation.Memory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLLA cell-based screen for splicing regulators identifies hnRNP LL as a distinct signal-induced repressor of CD45 variable exon 4.A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs).Signal- and development-dependent alternative splicing of LEF1 in T cells is controlled by CELF2.Loss of exon identity is a common mechanism of human inherited disease.Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signalingGlobal analysis of alternative splicing during T-cell activation.The impact of alternative splicing in vivo: mouse models show the way.Consequences of regulated pre-mRNA splicing in the immune system.Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation.TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cellsProtein kinase C-dependent control of Bcl-x alternative splicing.A new view of transcriptome complexity and regulation through the lens of local splicing variationsControl of alternative splicing in immune responses: many regulators, many predictions, much still to learnPosition-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells.In vivo selection of kinase-responsive RNA elements controlling alternative splicing.Selective induction of alternatively spliced FynT isoform by TNF facilitates persistent inflammatory responses in astrocytes.In silico to in vivo splicing analysis using splicing code models.Transcriptome-wide RNA interaction profiling reveals physical and functional targets of hnRNP L in human T cells.Context-dependent splicing regulation: exon definition, co-occurring motif pairs and tissue specificityAlternative splicing networks regulated by signaling in human T cells.HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing.Combinatorial control of signal-induced exon repression by hnRNP L and PSF.Modulating role of RNA structure in alternative splicing of a critical exon in the spinal muscular atrophy genes.A consensus CaMK IV-responsive RNA sequence mediates regulation of alternative exons in neurons.Regulation of alternative splicing of Bcl-x by IL-6, GM-CSF and TPA.
P2860
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P2860
A conserved signal-responsive sequence mediates activation-induced alternative splicing of CD45.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
A conserved signal-responsive ...... alternative splicing of CD45.
@en
type
label
A conserved signal-responsive ...... alternative splicing of CD45.
@en
prefLabel
A conserved signal-responsive ...... alternative splicing of CD45.
@en
P2093
P1433
P1476
A conserved signal-responsive ...... alternative splicing of CD45.
@en
P2093
Brandon Hahm
Brian Cannon
Caryn Rothrock
Kristen W Lynch
P304
P356
10.1016/S1097-2765(03)00434-9
P577
2003-11-01T00:00:00Z