Structural requirements of the dihydropyridine receptor alpha1S II-III loop for skeletal-type excitation-contraction coupling.
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3D Structure of the Dihydropyridine Receptor of Skeletal MuscleCa(V)1.1: The atypical prototypical voltage-gated Ca²⁺ channelThe junctional SR protein JP-45 affects the functional expression of the voltage-dependent Ca2+ channel Cav1.1Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractilityDomain cooperativity in the β1a subunit is essential for dihydropyridine receptor voltage sensing in skeletal muscle.Non-Ca2+-conducting Ca2+ channels in fish skeletal muscle excitation-contraction coupling.Excitation-contraction coupling from the 1950s into the new millennium.Ryanodine modification of RyR1 retrogradely affects L-type Ca(2+) channel gating in skeletal muscle.Ryanodine receptors: structure, expression, molecular details, and function in calcium release.Multiple loops of the dihydropyridine receptor pore subunit are required for full-scale excitation-contraction coupling in skeletal muscle.Cyclization of the intrinsically disordered α1S dihydropyridine receptor II-III loop enhances secondary structure and in vitro function.Accessibility of targeted DHPR sites to streptavidin and functional effects of binding on EC coupling.Fluorescence resonance energy transfer (FRET) indicates that association with the type I ryanodine receptor (RyR1) causes reorientation of multiple cytoplasmic domains of the dihydropyridine receptor (DHPR) α(1S) subunit.Three-dimensional localization of the α and β subunits and of the II-III loop in the skeletal muscle L-type Ca2+ channel.Effects of inserting fluorescent proteins into the alpha1S II-III loop: insights into excitation-contraction coupling.Differential contribution of skeletal and cardiac II-III loop sequences to the assembly of dihydropyridine-receptor arrays in skeletal muscle.Channelopathies in Cav1.1, Cav1.3, and Cav1.4 voltage-gated L-type Ca2+ channels.Ryanodine receptor calcium release channels: lessons from structure-function studies.The role of auxiliary subunits for the functional diversity of voltage-gated calcium channels.Physiological and pharmacological modulation of the embryonic skeletal muscle calcium channel splice variant CaV1.1eCore skeletal muscle ryanodine receptor calcium release complex.Dihydropyridine receptor (DHPR, CACNA1S) congenital myopathy.New factors contributing to dynamic calcium regulation in the skeletal muscle triad-a crowded placeCrystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.Effects of peptide C corresponding to the Glu724-Pro760 region of the II-III loop of the DHP (dihydropyridine) receptor alpha1 subunit on the domain- switch-mediated activation of RyR1 (ryanodine receptor 1) Ca2+ channels.Proper restoration of excitation-contraction coupling in the dihydropyridine receptor beta1-null zebrafish relaxed is an exclusive function of the beta1a subunit.The alpha(1S) III-IV loop influences 1,4-dihydropyridine receptor gating but is not directly involved in excitation-contraction coupling interactions with the type 1 ryanodine receptor.Divergent biophysical properties, gating mechanisms, and possible functions of the two skeletal muscle Ca(V)1.1 calcium channel splice variantsTwo distinct voltage-sensing domains control voltage sensitivity and kinetics of current activation in CaV1.1 calcium channels.The recombinant dihydropyridine receptor II-III loop and partly structured 'C' region peptides modify cardiac ryanodine receptor activity.Structural insights into binding of STAC proteins to voltage-gated calcium channels.Endoplasmic Reticulum-Plasma Membrane Contacts Regulate Cellular Excitability.STAC proteins associate to the IQ domain of CaV1.2 and inhibit calcium-dependent inactivation.Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of CaV1.1.
P2860
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P2860
Structural requirements of the dihydropyridine receptor alpha1S II-III loop for skeletal-type excitation-contraction coupling.
description
2003 nî lūn-bûn
@nan
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
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@zh
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name
Structural requirements of the ...... citation-contraction coupling.
@en
type
label
Structural requirements of the ...... citation-contraction coupling.
@en
prefLabel
Structural requirements of the ...... citation-contraction coupling.
@en
P2093
P2860
P356
P1476
Structural requirements of the ...... citation-contraction coupling.
@en
P2093
Bernhard E Flucher
Gerlinde Kugler
Manfred Grabner
Regina G Weiss
P2860
P304
P356
10.1074/JBC.M307538200
P407
P577
2003-11-18T00:00:00Z