Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage.
about
Methods to identify and characterize developmental neurotoxicity for human health risk assessment. III: pharmacokinetic and pharmacodynamic considerations.Ethanol, Zn2+ and insulin interact as progression factors to enhance DNA synthesis synergistically in the presence of Ca2+ and other cell cycle initiators in fibroblastsOver-expression of Nrf2 diminishes ethanol-induced oxidative stress and apoptosis in neural crest cells by inducing an antioxidant responsePreclinical studies of alcohol binge drinkingInhibition of insulin-like growth factor-1 receptor and IRS-2 signaling by ethanol in SH-SY5Y neuroblastoma cells.Dysregulation of TrkB phosphorylation and proBDNF protein in adenylyl cyclase 1 and 8 knockout mice in a model of fetal alcohol spectrum disorderDifluoromethylornithine (DFMO) reduces deficits in isolation-induced ultrasonic vocalizations and balance following neonatal ethanol exposure in ratsInduction of the Nrf2-driven antioxidant response by tert-butylhydroquinone prevents ethanol-induced apoptosis in cranial neural crest cells.Stabilization of Nrf2 protein by D3T provides protection against ethanol-induced apoptosis in PC12 cells.Effects of prenatal tobacco, alcohol and marijuana exposure on processing speed, visual-motor coordination, and interhemispheric transfer.Ethanol-induced attenuation of oxidative stress is unable to alter mRNA expression pattern of catalase, glutathione reductase, glutathione-S-transferase (GST1A), and superoxide dismutase (SOD3) enzymes in Japanese rice fish (Oryzias latipes) embryogNutrition implications for fetal alcohol spectrum disorder.An Update on Fetal Alcohol Syndrome-Pathogenesis, Risks, and Treatment.Low dose prenatal ethanol exposure induces anxiety-like behaviour and alters dendritic morphology in the basolateral amygdala of rat offspringSelective vulnerability of cerebellar granule neuroblasts and their progeny to drugs with abuse liability.The impact of maternal age on the effects of prenatal alcohol exposure on attentionAltered spatial learning and delay discounting in a rat model of human third trimester binge ethanol exposure.Alcohol teratogenesis: mechanisms of damage and strategies for intervention.Ethanol teratogenesis in Japanese medaka: effects at the cellular levelPreclinical and clinical pharmacology of alcohol dependence.The effects of binge alcohol exposure in the 2nd trimester on the estimated density of cerebral microvessels in near-term fetal sheep.Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per dayEthanol exposure of neonatal rats does not increase biomarkers of oxidative stress in isolated cerebellar granule neuronsLoss of motoneurons in the ventral compartment of the rat hypoglossal nucleus following early postnatal exposure to alcohol.Abnormal cortical thickness and brain-behavior correlation patterns in individuals with heavy prenatal alcohol exposure.DNA fragmentation during exposure of rat cerebella to ethanol under hypoxia imposed in vitro.Effects of moderate alcohol consumption on the central nervous system.Ethanol decreases Glial-Derived Neurotrophic Factor (GDNF) protein release but not mRNA expression and increases GDNF-stimulated Shc phosphorylation in the developing cerebellum.Ethanol induces cell death and cell cycle delay in cultures of pheochromocytoma PC12 cells.Purkinje cell deficits in nonhuman primates following weekly exposure to ethanol during gestation.Role of Oxidative Stress in Ethanol-induced Neurotoxicity in the Developing CerebellumEthanol influences on Bax translocation, mitochondrial membrane potential, and reactive oxygen species generation are modulated by vitamin E and brain-derived neurotrophic factor.Differential effects of ethanol on insulin-like growth factor-I receptor signaling.Potentiation of calcium-mediated stimulation of DNA synthesis by ethanol in human and mouse fibroblasts.Zinc supplementation does not attenuate alcohol-induced cerebellar Purkinje cell loss during the brain growth spurt period.MK-801 can exacerbate or attenuate behavioral alterations associated with neonatal alcohol exposure in the rat, depending on the timing of administration.Midline corpus callosum is a neuroanatomical focus of fetal alcohol damage.Melatonin (an antioxidant) does not ameliorate alcohol-induced Purkinje cell loss in the developing cerebellum.Administration of low doses of MK-801 during ethanol withdrawal in the developing rat pup attenuates alcohol's teratogenic effects.Age and gender differences in response to neonatal ethanol withdrawal and polyamine challenge in organotypic hippocampal cultures.
P2860
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P2860
Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Fetal alcohol syndrome: the vu ...... possible mechanisms of damage.
@en
type
label
Fetal alcohol syndrome: the vu ...... possible mechanisms of damage.
@en
prefLabel
Fetal alcohol syndrome: the vu ...... possible mechanisms of damage.
@en
P2093
P2860
P356
P1476
Fetal alcohol syndrome: the vu ...... possible mechanisms of damage.
@en
P2093
P2860
P2888
P304
P356
10.1007/BF02098878
P577
1994-12-01T00:00:00Z
P6179
1013513359