Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis.
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Involvement of GATA1 and Sp3 in the activation of the murine STING gene promoter in NIH3T3 cells.cGAS is essential for cellular senescence.DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity.Decreased Expression of TMEM173 Predicts Poor Prognosis in Patients with Hepatocellular CarcinomaThe host STING pathway at the interface of cancer and immunityCancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs.Decreased expression of STING predicts poor prognosis in patients with gastric cancer.Towards precision radiotherapy for use with immune checkpoint blockers.Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity.Activation of cGAS-dependent antiviral responses by DNA intercalating agents.The role of cGAS in innate immunity and beyond.Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.Nucleic acid sensing and innate immunity: signaling pathways controlling viral pathogenesis and autoimmunity.Adding STING to the Tale of Oncolytic Virotherapy.Rationale for stimulator of interferon genes-targeted cancer immunotherapy.Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis.Immune Diseases Associated with TREX1 and STING Dysfunction.Modulation of the Intratumoral Immune Landscape by Oncolytic Herpes Simplex Virus Virotherapy.Mechanisms regulating immune surveillance of cellular stress in cancer.Role of Type I and II Interferons in Colorectal Cancer and Melanoma.cGAS surveillance of micronuclei links genome instability to innate immunity.cGAS-STING Activation in the Tumor Microenvironment and Its Role in Cancer Immunity.Immunomodulatory and antitumor effects of type I interferons and their application in cancer therapy.Dysregulated cellular functions and cell stress pathways provide critical cues for activating and targeting natural killer cells to transformed and infected cells.Prospects for combined use of oncolytic viruses and CAR T-cells.cGAS/STING Pathway in Cancer: Jekyll and Hyde Story of Cancer Immune Response.Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer.Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway.STING Signaling in Cancer Cells: Important or Not?Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production.MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.Assessing the cGAS-cGAMP-STING Activity of Cancer Cells.Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.PARP1 depletion induces RIG-I-dependent signaling in human cancer cells.Targeting Cytosolic Nucleic Acid-Sensing Pathways for Cancer Immunotherapies.A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing.STING activation enhances cetuximab-mediated NK cell activation and DC maturation and correlates with HPV+ status in head and neck cancer.Virulent poxviruses inhibit DNA sensing by preventing STING activation.Emerging biomarkers for the combination of radiotherapy and immune checkpoint blockers.
P2860
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P2860
Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Deregulation of STING Signalin ...... Correlates With Tumorigenesis.
@en
type
label
Deregulation of STING Signalin ...... Correlates With Tumorigenesis.
@en
prefLabel
Deregulation of STING Signalin ...... Correlates With Tumorigenesis.
@en
P2093
P2860
P1433
P1476
Deregulation of STING Signalin ...... Correlates With Tumorigenesis.
@en
P2093
Glen N Barber
Hiroyasu Konno
Jeonghyun Ahn
Tianli Xia
P2860
P304
P356
10.1016/J.CELREP.2015.12.029
P577
2015-12-30T00:00:00Z