about
Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans modelsTetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical ResearchTetracycline antibiotics impair mitochondrial function and its experimental use confounds researchType 5 adenylyl cyclase disruption leads to enhanced exercise performanceAn automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging.A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans.Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle.A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.Metabolomics analysis uncovers that dietary restriction buffers metabolic changes associated with aging in Caenorhabditis elegans.Transcriptional coregulators: fine-tuning metabolism.Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer.NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.An evolutionarily conserved role for the aryl hydrocarbon receptor in the regulation of movement.The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents.Emerging roles of the corepressors NCoR1 and SMRT in homeostasis.Mitonuclear protein imbalance as a conserved longevity mechanism.Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.NAD⁺ metabolism: a therapeutic target for age-related metabolic disease.The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease.Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging.A multiscale study of the role of dynamin in the regulation of glucose uptake.Label-free three-dimensional imaging of Caenorhabditis elegans with visible optical coherence microscopy.The Movement Tracker: A Flexible System for Automated Movement Analysis in Invertebrate Model Organisms.
P50
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P50
description
onderzoeker
@nl
name
Laurent Mouchiroud
@ast
Laurent Mouchiroud
@en
Laurent Mouchiroud
@es
Laurent Mouchiroud
@sl
type
label
Laurent Mouchiroud
@ast
Laurent Mouchiroud
@en
Laurent Mouchiroud
@es
Laurent Mouchiroud
@sl
prefLabel
Laurent Mouchiroud
@ast
Laurent Mouchiroud
@en
Laurent Mouchiroud
@es
Laurent Mouchiroud
@sl