Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis.
about
RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivoCurrent status and prospect of lung cancer gene therapyProtein kinase C-alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasionH-Ras increases urokinase expression and cell invasion in genetically modified human astrocytes through Ras/Raf/MEK signaling pathwayTyrosine-kinase inhibition results in EGFR clustering at focal adhesions and consequent exocytosis in uPAR down-regulated cells of head and neck cancers.MMP-9, uPAR and cathepsin B silencing downregulate integrins in human glioma xenograft cells in vitro and in vivo in nude mice.Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells.Antimetastatic potential of PAI-1-specific RNA aptamers.RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth.α3β1 integrin promotes radiation-induced migration of meningioma cellsCathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in gliomaSpherical cancer models in tumor biology.Maspin regulates hypoxia-mediated stimulation of uPA/uPAR complex in invasive breast cancer cellsDemethylation-linked activation of urokinase plasminogen activator is involved in progression of prostate cancer.Down-regulation of uPAR and uPA activates caspase-mediated apoptosis and inhibits the PI3K/AKT pathway.Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 3: brain tumor invasiveness.Urokinase-type plasminogen activator receptor (uPAR)-mediated regulation of WNT/β-catenin signaling is enhanced in irradiated medulloblastoma cells.Molecular optical imaging: applications leading to the development of present day therapeuticsIntraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.Inhibition of histone deacetylase activity promotes invasion of human cancer cells through activation of urokinase plasminogen activator.Resveratrol Induces Glioma Cell Apoptosis through Activation of Tristetraprolin.uPAR and cathepsin B shRNA impedes TGF-β1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway.Radiation-induced hypomethylation triggers urokinase plasminogen activator transcription in meningioma cellsRNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo.Turning the gene tap off; implications of regulating gene expression for cancer therapeutics.RNAi-mediated downregulation of radiation-induced MMP-9 leads to apoptosis via activation of ERK and Akt in IOMM-Lee cells.Antiangiogenic therapy in brain tumors.Multifunctional roles of urokinase plasminogen activator (uPA) in cancer stemness and chemoresistance of pancreatic cancer.SPARC overexpression combined with radiation retards angiogenesis by suppressing VEGF-A via miR‑410 in human neuroblastoma cells.Sphingosine-1-phosphate regulates glioblastoma cell invasiveness through the urokinase plasminogen activator system and CCN1/Cyr61Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases.Urokinase type plasminogen activator receptor (uPAR) as a new therapeutic target in cancer.Urokinase plasminogen activator system as a potential target for cancer therapy.Blockade of vascular endothelial growth factor receptors by tivozanib has potential anti-tumour effects on human glioblastoma cellsSitimagene ceradenovec: a gene-based drug for the treatment of operable high-grade glioma.Systematic review of protein biomarkers of invasive behavior in glioblastoma.Chimeric adeno-associated virus and bacteriophage: a potential targeted gene therapy vector for malignant glioma.Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells.Synergistic effects of arsenic trioxide and silibinin on apoptosis and invasion in human glioblastoma U87MG cell line.
P2860
Q24539093-2364AB72-D4AB-458D-AF52-F6D9CA1B1C5EQ26825190-BBB2A79F-AF02-493A-8DA2-5BFA402FDD57Q30440947-EF632FB4-8C0E-45BE-88B6-1FF8915D4A2CQ30441619-22AF12D5-4EE5-4228-B758-DEE56C59369BQ30482688-0E815B49-7C41-4B47-A58E-6475DC854DA3Q33640030-51F9D2FC-945E-4C41-9841-1FBCA2A5B3B3Q34057949-71FF396B-3D6C-4DE8-9F42-F438AE15FEF8Q34167905-850E55CD-4BB6-4808-86E0-B7D2D5AE664AQ34601099-8B8B58DB-C563-4EC4-A40E-FD3C0A50A55CQ34902827-DFE868C1-954F-4A5D-881D-C36BBEA4EAFDQ34987834-69C0FBFE-2E96-41F1-921E-7FE3C1627A49Q35023931-0B25904D-0C85-4025-887D-67D3D0996142Q35220266-674E96DB-D939-4EF6-B6E1-9A3BCF7C9849Q35699282-E27F5FFD-EB38-48AB-96DF-36A99464D49BQ35867494-D341D261-68F4-4BEE-B7D5-ECACFB2D38A6Q35918449-EDD3298A-A29F-45C8-9C41-7ED88591ACDFQ36016967-D0D90CDA-7F62-457C-991B-2ED993D2ADF3Q36129726-07228794-3885-48CD-8B54-EB35F3777117Q36274412-8C594AE6-678B-4557-A550-CE6EC158A51EQ36302249-3FD5DB6A-996B-4C7F-8D2D-12FA4E856FF2Q36356758-DC692A74-8696-4A6F-A896-3FFE6B0CBDCAQ36525170-D4D2DF52-5ABA-4E77-A272-180D2A3721C8Q36629426-8D892BD0-058B-48D9-BC41-029846D02793Q36676608-D54F08DC-9055-4169-8E01-B40A2EFCEDBFQ36955412-9AA30EEC-B55D-45CD-8CD3-C54D5C381894Q36994041-41265A86-B807-4E9A-B272-2F004A245CDAQ37020853-9357AC91-6AE3-4FD1-BDA6-6C8060252CEAQ37129915-189E27C8-5E3D-4378-A5F6-B5236D45C55FQ37131462-E122C434-AFBD-4156-9260-37B6CA547990Q37252700-BDCD9BA6-DD06-4EB6-8B6D-1B3448BC0016Q37255447-C516F819-133B-4F5A-A9FB-1B947A8EF386Q37419308-706AAC49-3D0F-4568-B006-98D54CF21198Q37432551-07AA601F-D8C3-437D-812A-3D2125D241AEQ37630593-B781848F-FE4E-4661-B7B4-B2FF80A43C46Q37695245-D8608A03-2ABB-4D03-AFA0-68C18B7D7F8CQ37818222-9EE0F6DF-E5F4-4770-944A-4370BFD798D3Q38165795-3B0F8C11-92BC-445F-AB7F-5AA7A8882244Q38265614-29F43052-61B4-4C72-B375-BA9E8AE8E1F1Q38340838-DB6F8D0B-B9B8-4C6F-A697-0F04E350F65BQ39463690-0D92AAFB-C8BC-48E2-B144-6AF6B965C613
P2860
Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Expression of antisense uPAR a ...... umor growth, and angiogenesis.
@en
type
label
Expression of antisense uPAR a ...... umor growth, and angiogenesis.
@en
prefLabel
Expression of antisense uPAR a ...... umor growth, and angiogenesis.
@en
P2093
P2860
P356
P1433
P1476
Expression of antisense uPAR a ...... tumor growth, and angiogenesis
@en
P2093
Dzung H Dinh
Jasti S Rao
Khawar Siddique
Meena Gujrati
Niranjan Yanamandra
Sajani S Lakka
William C Olivero
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206535
P407
P577
2003-09-01T00:00:00Z
P5875
P6179
1002388420