Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells - Wikidata - awgldk - TriplyDB

Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells

Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells

http://www.wikidata.org/entity/Q40638785

about

Functional sialylated O-glycan to platelet aggregation on Aggrus (T1alpha/Podoplanin) molecules expressed in Chinese hamster ovary cells MUC1 expression by human airway epithelial cells mediates Pseudomonas aeruginosa adhesion.Altered O-glycosylation and sulfation of airway mucins associated with cystic fibrosis.Mucin-type O-glycosylation--putting the pieces together.Human gastric mucins differently regulate Helicobacter pylori proliferation, gene expression and interactions with host cells.The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.Aeromonas salmonicida binds differentially to mucins isolated from skin and intestinal regions of Atlantic salmon in an N-acetylneuraminic acid-dependent manner.Multiple enzyme approach for the characterization of glycan modifications on the C-terminus of the intestinal MUC2mucin.Characterization of two different endo-alpha-N-acetylgalactosaminidases from probiotic and pathogenic enterobacteria, Bifidobacterium longum and Clostridium perfringens.Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis.The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.Lipopeptide-Coated Iron Oxide Nanoparticles as Potential Glycoconjugate-Based Synthetic Anticancer Vaccines.Human synovial lubricin expresses sialyl Lewis x determinant and has L-selectin ligand activity Interactions between the breast cancer-associated MUC1 mucins and C-type lectin characterized by optical tweezers.Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer Aberrant O-glycosylation and anti-glycan antibodies in an autoimmune disease IgA nephropathy and breast adenocarcinoma.Optimisation of the cellular metabolism of glycosylation for recombinant proteins produced by Mammalian cell systems.Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells.Cervical mucins carry alpha(1,2)fucosylated glycans that partly protect from experimental vaginal candidiasis.The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9.Cellular and molecular biology of airway mucins.Function of the CysD domain of the gel-forming MUC2 mucin.MUC1 in hematological malignancies.Characterisation and internalisation of recombinant humanised HMFG-1 antibodies against MUC1.Increased understanding of the biochemistry and biosynthesis of MUC2 and other gel-forming mucins through the recombinant expression of their protein domains.Metabolic glycoengineering through the mammalian GalNAc salvage pathway.Interactions of mucins with the Tn or Sialyl Tn cancer antigens including MUC1 are due to GalNAc-GalNAc interactions.Cleavage in the GDPH sequence of the C-terminal cysteine-rich part of the human MUC5AC mucin.The levels of Brachyspira hyodysenteriae binding to porcine colonic mucins differ between individuals, and binding is increased to mucins from infected pigs with de novo MUC5AC synthesis.Tumor-Derived Microvesicles Modulate Antigen Cross-Processing via Reactive Oxygen Species-Mediated Alkalinization of Phagosomal Compartment in Dendritic Cells.Transforming growth factor-β1 is constitutively secreted by Chinese hamster ovary cells and is functional in human cells.Latest developments in MUC1 immunotherapy.Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2-6 sialic acids

P2860

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P2860

Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells

http://www.wikidata.org/entity/Q40638785

description

2003 nî lūn-bûn

@nan

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

2003年论文

@zh

2003年论文

@zh-cn

name

Recombinant MUC1 mucin with a ...... in Chinese-hamster ovary cells

@en

type

label

Recombinant MUC1 mucin with a ...... in Chinese-hamster ovary cells

@en

prefLabel

Recombinant MUC1 mucin with a ...... in Chinese-hamster ovary cells

@en

P1433

Q40638785-078B30A8-94E4-46EA-AAFB-253A0B6C3F9D

P1476

Q40638785-451F30E7-18A9-4950-BD95-F7A490E98F13

P2093

Q40638785-283CEAAB-9D17-47CF-843F-66A251D6C464

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Q40638785-96277AC4-ADE5-45F0-9418-80045EE6C34E

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Q40638785-F8A2174F-72A1-42F4-B0D3-11141BB07CB1

Q40638785-FE607AB1-156B-4340-804E-E7DFD53F3610

P2860

Q40638785-12A131B2-7B7B-418F-AFE4-0EAFFC2F7A75

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P304

Q40638785-70D1A866-5D85-431A-BFB5-E3BAE16DED9E

P31

Q40638785-098C9E6B-6A04-416E-BBA8-D6904C7D9A19

P356

Q40638785-5AF70437-DEB3-4F3A-8C76-E478EE1CD307

P407

Q40638785-4FE8C1D3-7985-451E-A5B5-C6C9D92E574C

P433

Q40638785-3E2D2928-C106-4E4C-8E7F-CF2101DDEF76

P478

Q40638785-B133D52C-CDC0-4010-B88E-EB6FA2156324

P577

Q40638785-20D97505-F402-44BD-9FA7-CCFBCDEC104F

P698

Q40638785-7117432D-5481-4F7C-8316-A64E668E9EEF

P921

Q40638785-4C3E5E25-D470-43F3-B5A2-7E2EF930DC0D

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P932

Q40638785-1D6D745F-501E-472B-8F58-A99C67087989

P356

P1433

Biochemical Journal

P1476

Recombinant MUC1 mucin with a ...... in Chinese-hamster ovary cells

@en

P2093

Fredrik J Olson

http://www.w3.org/2001/XMLSchema#string

Gianfranco Picco

http://www.w3.org/2001/XMLSchema#string

Gunnar C Hansson

http://www.w3.org/2001/XMLSchema#string

Hasse Karlsson

http://www.w3.org/2001/XMLSchema#string

Joy Burchell

http://www.w3.org/2001/XMLSchema#string

Joyce Taylor-Papadimitriou

http://www.w3.org/2001/XMLSchema#string

Malin Bäckström

http://www.w3.org/2001/XMLSchema#string

Rosalind Graham

http://www.w3.org/2001/XMLSchema#string

Thomas Link

http://www.w3.org/2001/XMLSchema#string

Thomas Noll

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin

Identification of two highly sialylated human tear-fluid DMBT1 isoforms: the major high-molecular-mass glycoproteins in human tears

MUC1, the renaissance molecule

Recombinant MUC1 probe authentically reflects cell-specific O-glycosylation profiles of endogenous breast cancer mucin. High density and prevalent core 2-based glycosylation.

The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.

Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein.

Effect of modification of carbohydrate side chains on the reactivity of antibodies with core-protein epitopes of the MUC1 gene product.

MUC1 glycoforms in breast cancer--cell line T47D as a model for carcinoma-associated alterations of 0-glycosylation.

Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells.

P304

677-686

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P31

scholarly article

P356

10.1042/BJ20031130

http://www.w3.org/2001/XMLSchema#string

P407

P433

Pt 3

http://www.w3.org/2001/XMLSchema#string

P478

376

http://www.w3.org/2001/XMLSchema#string

P577

2003-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

12950230

http://www.w3.org/2001/XMLSchema#string

P921

alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->3)-D-GalpNAc

beta-D-Gal-(1->3)-[beta-D-GlcNAc-(1->6)]-D-GalNAc

P932

1223800

http://www.w3.org/2001/XMLSchema#string