Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells
about
Functional sialylated O-glycan to platelet aggregation on Aggrus (T1alpha/Podoplanin) molecules expressed in Chinese hamster ovary cellsMUC1 expression by human airway epithelial cells mediates Pseudomonas aeruginosa adhesion.Altered O-glycosylation and sulfation of airway mucins associated with cystic fibrosis.Mucin-type O-glycosylation--putting the pieces together.Human gastric mucins differently regulate Helicobacter pylori proliferation, gene expression and interactions with host cells.The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.Aeromonas salmonicida binds differentially to mucins isolated from skin and intestinal regions of Atlantic salmon in an N-acetylneuraminic acid-dependent manner.Multiple enzyme approach for the characterization of glycan modifications on the C-terminus of the intestinal MUC2mucin.Characterization of two different endo-alpha-N-acetylgalactosaminidases from probiotic and pathogenic enterobacteria, Bifidobacterium longum and Clostridium perfringens.Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis.The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.Lipopeptide-Coated Iron Oxide Nanoparticles as Potential Glycoconjugate-Based Synthetic Anticancer Vaccines.Human synovial lubricin expresses sialyl Lewis x determinant and has L-selectin ligand activityInteractions between the breast cancer-associated MUC1 mucins and C-type lectin characterized by optical tweezers.Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancerAberrant O-glycosylation and anti-glycan antibodies in an autoimmune disease IgA nephropathy and breast adenocarcinoma.Optimisation of the cellular metabolism of glycosylation for recombinant proteins produced by Mammalian cell systems.Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells.Cervical mucins carry alpha(1,2)fucosylated glycans that partly protect from experimental vaginal candidiasis.The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9.Cellular and molecular biology of airway mucins.Function of the CysD domain of the gel-forming MUC2 mucin.MUC1 in hematological malignancies.Characterisation and internalisation of recombinant humanised HMFG-1 antibodies against MUC1.Increased understanding of the biochemistry and biosynthesis of MUC2 and other gel-forming mucins through the recombinant expression of their protein domains.Metabolic glycoengineering through the mammalian GalNAc salvage pathway.Interactions of mucins with the Tn or Sialyl Tn cancer antigens including MUC1 are due to GalNAc-GalNAc interactions.Cleavage in the GDPH sequence of the C-terminal cysteine-rich part of the human MUC5AC mucin.The levels of Brachyspira hyodysenteriae binding to porcine colonic mucins differ between individuals, and binding is increased to mucins from infected pigs with de novo MUC5AC synthesis.Tumor-Derived Microvesicles Modulate Antigen Cross-Processing via Reactive Oxygen Species-Mediated Alkalinization of Phagosomal Compartment in Dendritic Cells.Transforming growth factor-β1 is constitutively secreted by Chinese hamster ovary cells and is functional in human cells.Latest developments in MUC1 immunotherapy.Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2-6 sialic acids
P2860
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P2860
Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Recombinant MUC1 mucin with a ...... in Chinese-hamster ovary cells
@en
type
label
Recombinant MUC1 mucin with a ...... in Chinese-hamster ovary cells
@en
prefLabel
Recombinant MUC1 mucin with a ...... in Chinese-hamster ovary cells
@en
P2093
P2860
P921
P356
P1433
P1476
Recombinant MUC1 mucin with a ...... in Chinese-hamster ovary cells
@en
P2093
Fredrik J Olson
Gianfranco Picco
Gunnar C Hansson
Hasse Karlsson
Joy Burchell
Joyce Taylor-Papadimitriou
Malin Bäckström
Rosalind Graham
Thomas Link
Thomas Noll
P2860
P304
P356
10.1042/BJ20031130
P407
P577
2003-12-01T00:00:00Z