A method for allelic replacement in Francisella tularensis.
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The complete genome sequence of Francisella tularensis, the causative agent of tularemiaFrancisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for VirulenceDissection of Francisella-Host Cell Interactions in Dictyostelium discoideum.Importance of PdpC, IglC, IglI, and IglG for modulation of a host cell death pathway induced by Francisella tularensisTwin RNA polymerase-associated proteins control virulence gene expression in Francisella tularensisMassively parallel delivery of large cargo into mammalian cells with light pulses.Characterization of the siderophore of Francisella tularensis and role of fslA in siderophore productionIdentification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection modelIn vivo Himar1-based transposon mutagenesis of Francisella tularensis.RipA, a cytoplasmic membrane protein conserved among Francisella species, is required for intracellular survivalGlobal transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis.Small molecule control of virulence gene expression in Francisella tularensisIdentification of trkH, encoding a potassium uptake protein required for Francisella tularensis systemic dissemination in mice.Molecular complexity orchestrates modulation of phagosome biogenesis and escape to the cytosol of macrophages by Francisella tularensisDifferential ability of novel attenuated targeted deletion mutants of Francisella tularensis subspecies tularensis strain SCHU S4 to protect mice against aerosol challenge with virulent bacteria: effects of host background and route of immunization.The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis.Francisella tularensis Schu S4 O-antigen and capsule biosynthesis gene mutants induce early cell death in human macrophages.Identification of a putative chaperone involved in stress resistance and virulence in Francisella tularensisFrancisella tularensis DeltapyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in vivo.Pivotal role of the Francisella tularensis heat-shock sigma factor RpoH.Characterization of the pathogenicity island protein PdpA and its role in the virulence of Francisella novicidaMacrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.IglC and PdpA are important for promoting Francisella invasion and intracellular growth in epithelial cellsCharacterization of the O-antigen polymerase (Wzy) of Francisella tularensis.The role of MglA for adaptation to oxidative stress of Francisella tularensis LVS.Lipidation of the FPI protein IglE contributes to Francisella tularensis ssp. novicida intramacrophage replication and virulence.A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine.DotU and VgrG, core components of type VI secretion systems, are essential for Francisella LVS pathogenicity3-Deoxy-D-manno-octulosonic acid (Kdo) hydrolase identified in Francisella tularensis, Helicobacter pylori, and Legionella pneumophila.Identification of mechanisms for attenuation of the FSC043 mutant of Francisella tularensis SCHU S4.Generation and characterization of an attenuated mutant in a response regulator gene of Francisella tularensis live vaccine strain (LVS).Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia.Utilization of an unstable plasmid and the I-SceI endonuclease to generate routine markerless deletion mutants in Francisella tularensis.The Francisella tularensis LVS ΔpdpC mutant exhibits a unique phenotype during intracellular infectionIron content differs between Francisella tularensis subspecies tularensis and subspecies holarctica strains and correlates to their susceptibility to H(2)O(2)-induced killingVirulence of Francisella spp. in chicken embryos.Construction and characterization of an attenuated purine auxotroph in a Francisella tularensis live vaccine strainThe francisella tularensis proteome and its recognition by antibodies.Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulenceA ΔclpB mutant of Francisella tularensis subspecies holarctica strain, FSC200, is a more effective live vaccine than F. tularensis LVS in a mouse respiratory challenge model of tularemia.
P2860
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P2860
A method for allelic replacement in Francisella tularensis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
A method for allelic replacement in Francisella tularensis.
@en
type
label
A method for allelic replacement in Francisella tularensis.
@en
prefLabel
A method for allelic replacement in Francisella tularensis.
@en
P2093
P2860
P1476
A method for allelic replacement in Francisella tularensis.
@en
P2093
Alexander Mokrievich
Igor Golovliov
Vitaly Pavlov
P2860
P304
P356
10.1016/S0378-1097(03)00313-6
P577
2003-05-01T00:00:00Z