Notch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression.
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MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiationActivated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitorsIntracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activationRbm15 modulates Notch-induced transcriptional activation and affects myeloid differentiationAberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertilityPotential autoregulation of transcription factor PU.1 by an upstream regulatory elementJAK2 V617F-dependent upregulation of PU.1 expression in the peripheral blood of myeloproliferative neoplasm patientsFucose-deficient hematopoietic stem cells have decreased self-renewal and aberrant marrow niche occupancy.Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.Mast cell plasticity and sphingosine-1-phosphate in immunity, inflammation and cancer.Cellular target genes of Epstein-Barr virus nuclear antigen 2.GATA2(-/-) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitmentThe zebrafish reveals dependence of the mast cell lineage on Notch signaling in vivo.Myeloid-Specific Blockade of Notch Signaling Attenuates Choroidal Neovascularization through Compromised Macrophage Infiltration and Polarization in MiceNotch signaling in developmental and tumor angiogenesis.Tracking hematopoiesis at the single cell level.Jagged-1 Signaling in the Bone Marrow Microenvironment Promotes Endothelial Progenitor Cell Expansion and Commitment of CD133+ Human Cord Blood Cells for Postnatal Vasculogenesis.Notch pathway activation targets AML-initiating cell homeostasis and differentiation.Notch-dependent control of myelopoiesis is regulated by fucosylationNotch signaling in differentiation and function of dendritic cells.Notch signaling in embryonic and adult myelopoiesis.Notch and wingless signaling cooperate in regulation of dendritic cell differentiationDown-regulation of PLCγ2-β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer.PU.1 and partners: regulation of haematopoietic stem cell fate in normal and malignant haematopoiesis.Regulation of Notch signaling during T- and B-cell development by O-fucose glycans.Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons.Regulation of dendritic cell differentiation and function by Notch and Wnt pathways.Notch signaling: switching an oncogene to a tumor suppressor.The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity.Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSC expansion.Myeloproliferation and hematopoietic stem cell dysfunction due to defective Notch receptor modification by O-fucose glycans.Pleiotropic roles of Notch signaling in normal, malignant, and developmental hematopoiesis in the human.Novel drug therapies in myeloid leukemia.Myeloid-derived suppressor cells in B cell malignancies.The deposition of Notch1 in hepatitis B virus-associated nephropathy and its role in hepatitis B virus X protein-induced epithelial-mesenchymal transdifferentiation and immunity disorder in renal tubular epithelial cells.Approaches for targeting self-renewal pathways in cancer stem cells: implications for hematological treatments.Notch activation inhibits AML growth and survival: a potential therapeutic approach.The NOTCH pathway contributes to cell fate decision in myelopoiesisNotch1 activation reduces proliferation in the multipotent hematopoietic progenitor cell line FDCP-mix through a p53-dependent pathway but Notch1 effects on myeloid and erythroid differentiation are independent of p53.Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias.
P2860
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P2860
Notch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Notch signaling induces multil ...... up-regulates PU.1 expression.
@en
type
label
Notch signaling induces multil ...... up-regulates PU.1 expression.
@en
prefLabel
Notch signaling induces multil ...... up-regulates PU.1 expression.
@en
P2093
P1476
Notch signaling induces multil ...... d up-regulates PU.1 expression
@en
P2093
Hella Kohlhof
Nikolaus Rieber
Ursula Just
P304
P356
10.4049/JIMMUNOL.170.11.5538
P407
P577
2003-06-01T00:00:00Z