Specific inhibition of pathological prion protein accumulation by small interfering RNAs.
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Hot spots in prion protein for pathogenic conversionLentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected miceAnti-prion activity of Brilliant Blue GCellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein.Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease.From high-throughput cell culture screening to mouse model: identification of new inhibitor classes against prion disease.Downregulation of lentivirus-mediated ILK RNAi on tractional force generation in human retinal Müller cells.Mouse neuronal cells expressing exogenous bovine PRNP and simultaneous downregulation of endogenous mouse PRNP using siRNAs.Search for a prion-specific nucleic acid.Diphenylpyrazole-derived compounds increase survival time of mice after prion infection.Prion infection of epithelial Rov cells is a polarized event.Silencing the activity and proliferative properties of the human EagI Potassium Channel by RNA Interference.Suppression of prion protein in livestock by RNA interference.Recent advances in prion chemotherapeutics.Rational targeting for prion therapeutics.Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice.siRNA as a route to new cancer therapies.PrPc does not mediate internalization of PrPSc but is required at an early stage for de novo prion infection of Rov cells.RNA knockdown as a potential therapeutic strategy in Parkinson's disease.Increased locomotor activity and non-selective attention and impaired learning ability in SD rats after lentiviral vector-mediated RNA interference of Homer 1a in the brainPrion proteins: a biological role beyond prion diseases.Therapeutic approaches for prion disorders.Susceptibility of cell substrates to PrPSc infection and safety control measures related to biological and biotherapeutical products.Therapy for prion diseases: Insights from the use of RNA interference.Modelling neurodegeneration in prion disease - applications for drug development.Small RNA drugs for prion disease: a new frontier.Treatment of SMB-S15 Cells with Resveratrol Efficiently Removes the PrP(Sc) Accumulation In Vitro and Prion Infectivity In Vivo.PrP(C) regulates epidermal growth factor receptor function and cell shape dynamics in Neuro2a cells.Inhibition of PrPSc formation by lentiviral gene transfer of PrP containing dominant negative mutations.Efficient knockdown of human prnp mRNA expression levels using hybrid hammerhead ribozymes.Dual MicroRNA to Cellular Prion Protein Inhibits Propagation of Pathogenic Prion Protein in Cultured Cells.Scrapie protein degradation by cysteine proteases in CD11c+ dendritic cells and GT1-1 neuronal cells.Progress and problems in the biology, diagnostics, and therapeutics of prion diseases.Specific inhibition of gene expression and transactivation functions of hepatitis B virus X protein and c-myc by small interfering RNAs.Clustering of cellular prion protein induces ERK1/2 and stathmin phosphorylation in GT1-7 neuronal cells.Divergent expression of cellular prion protein on blood cells of human and nonhuman primates.
P2860
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P2860
Specific inhibition of pathological prion protein accumulation by small interfering RNAs.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Specific inhibition of pathological prion protein accumulation by small interfering RNAs.
@en
type
label
Specific inhibition of pathological prion protein accumulation by small interfering RNAs.
@en
prefLabel
Specific inhibition of pathological prion protein accumulation by small interfering RNAs.
@en
P2093
P356
P1476
Specific inhibition of pathological prion protein accumulation by small interfering RNAs.
@en
P2093
Joelle Chabry
Mathieu Marella
Nathalie Daude
P304
P356
10.1242/JCS.00494
P407
P577
2003-05-20T00:00:00Z