Enhancer and promoter elements directing activation and glucocorticoid repression of the alpha 1-fetoprotein gene in hepatocytes.
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Regulation of alpha-fetoprotein expression by Nkx2.8A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingersMolecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gammaFunctional analysis of developmentally regulated chromatin-hypersensitive domains carrying the alpha 1-fetoprotein gene promoter and the albumin/alpha 1-fetoprotein intergenic enhancerSumoylation of CCAAT/enhancer-binding protein alpha and its functional roles in hepatocyte differentiationThe alpha1-fetoprotein locus is activated by a nuclear receptor of the Drosophila FTZ-F1 familyThe fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 elementATBF1, a multiple-homeodomain zinc finger protein, selectively down-regulates AT-rich elements of the human alpha-fetoprotein gene.Hepatocyte dedifferentiation and extinction is accompanied by a block in the synthesis of mRNA coding for the transcription factor HNF1/LFB1Expression from the tyrosine aminotransferase promoter (nt -350 to +1) is liver-specific and dependent on the binding of both liver-enriched and ubiquitous trans-acting factors.Methylation of an alpha-foetoprotein gene intragenic site modulates gene activity.Combinatorial control of positive and negative, upstream and intragenic regulatory DNA domains of the mouse alpha 1-foetoprotein geneHighly inducible expression from vectors containing multiple GRE's in CHO cells overexpressing the glucocorticoid receptor.Telomerase inhibition decreases alpha-fetoprotein expression and secretion by hepatocellular carcinoma cell lines: in vitro and in vivo study.Derepression of a mouse alpha-fetoprotein expression vector in COS-1 cells by amplification of specific cis-acting sequences of the AFP promoter.alpha-Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration.The ontogeny of alpha-fetoprotein gene expression in the mouse gastrointestinal tractA novel hepatocytic transcription factor that binds the alpha-fetoprotein promoter-linked coupling element.Transcription of the histone H5 gene is regulated by three differentiation-specific enhancers.Transcription of the mouse secretory protease inhibitor p12 gene is activated by the developmentally regulated positive transcription factor Sp1Repression of the alpha-fetoprotein gene promoter by progesterone and chimeric receptors in the presence of hormones and antihormonesc-Ha-ras down regulates the alpha-fetoprotein gene but not the albumin gene in human hepatoma cells.Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1.Characterization of a thyroid-specific enhancer located 5.5 kilobase pairs upstream of the human thyroid peroxidase geneThe rat albumin promoter: cooperation with upstream elements is required when binding of APF/HNF1 to the proximal element is partially impaired by mutation or bacterial methylationGlucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcriptionInteraction of a hepatoma-specific nuclear factor with transcription-regulatory sequences of the human alpha-fetoprotein and albumin genes.Hepatic acute phase reaction in vivo and in vitro.Retinoic acid mediates down-regulation of the alpha-fetoprotein gene through decreased expression of hepatocyte nuclear factors.JNK-mediated phosphorylation of paxillin in adhesion assembly and tension-induced cell death by the adenovirus death factor E4orf4.Loss of function of vascular smooth muscle cells by nitric oxide-dependent and -independent interactions with tumorigenic cells.The alpha-foetoprotein proximal enhancer: localization, cell specificity and modulation by dexamethasone.Similar effects of adenovirus E1A and glucocorticoid hormones on the expression of the metalloprotease stromelysin.The anti-inflammatory activity of glucocorticoids.Repression mechanisms of v-ERBA and other members of the steroid receptor superfamily.Involvement of c-Jun in the control of glucocorticoid receptor transcriptional activity during development of chicken retinal tissue.Negative regulation of transcription in eukaryotes.Role of the negative glucocorticoid regulatory element in glucocorticoid repression of the human osteocalcin promoter.Glucocorticoid hormones reduce the expression of major histocompatibility class I antigens on human epithelial cells.Members of the CAAT/enhancer-binding protein, hepatocyte nuclear factor-1 and nuclear factor-1 families can differentially modulate the activities of the rat alpha-fetoprotein promoter and enhancer.
P2860
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P2860
Enhancer and promoter elements directing activation and glucocorticoid repression of the alpha 1-fetoprotein gene in hepatocytes.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Enhancer and promoter elements ...... toprotein gene in hepatocytes.
@en
type
label
Enhancer and promoter elements ...... toprotein gene in hepatocytes.
@en
prefLabel
Enhancer and promoter elements ...... toprotein gene in hepatocytes.
@en
P2093
P2860
P356
P1476
Enhancer and promoter elements ...... toprotein gene in hepatocytes.
@en
P2093
Bélanger L
Chevrette M
Gingras MC
P2860
P304
P356
10.1128/MCB.8.4.1398
P407
P577
1988-04-01T00:00:00Z