Autoimmune disease-associated haplotypes of BLK exhibit lowered thresholds for B cell activation and expansion of Ig class-switched B cells.
about
The SLE variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 through impairment of the SH3 domain function.The Genotype and Phenotype (GaP) registry: a living biobank for the analysis of quantitative traits.Genetics of autoimmune diseases: perspectives from genome-wide association studies.The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans.DNA-reactive B cells in lupus.Abnormal B-cell development in Systemic Lupus Erythematosus: what the genetics tell us.CD4+ and B Lymphocyte Expression Quantitative Traits at Rheumatoid Arthritis Risk Loci in Patients With Untreated Early Arthritis: Implications for Causal Gene Identification.Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome.The genetics of Kawasaki disease.Plasma Cell Differentiation Pathways in Systemic Lupus Erythematosus.
P2860
Q30009028-036DC593-9066-4720-8F21-24A21EA4DCAAQ38607446-4F51E960-7402-4EA2-9164-AE42B8E33A4FQ38726782-65079BAA-FA3D-4F41-8133-19E9EDF19866Q38732751-40052A3C-27CB-4400-A4CD-255601712850Q38922669-50B15B3A-A9E0-4B40-9D84-0505E3FBCE2FQ47365066-B69BC33B-11CD-4131-81BF-0724EA15CB69Q49376742-D799AE04-93CD-4B3E-AA31-59ED72864368Q49630908-981A7807-2D18-4329-9981-241ED29BDA0BQ49892043-C8848F94-E449-4448-829A-5BC965C05E6BQ55266542-0D85A1BC-4D7F-40B3-8F30-59628D47D015
P2860
Autoimmune disease-associated haplotypes of BLK exhibit lowered thresholds for B cell activation and expansion of Ig class-switched B cells.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Autoimmune disease-associated ...... of Ig class-switched B cells.
@en
type
label
Autoimmune disease-associated ...... of Ig class-switched B cells.
@en
prefLabel
Autoimmune disease-associated ...... of Ig class-switched B cells.
@en
P2093
P2860
P356
P1476
Autoimmune disease-associated ...... of Ig class-switched B cells.
@en
P2093
Andrew Shih
Annette T Lee
Betty Diamond
Brandon E Armstead
Kim R Simpfendorfer
Mark Curran
Peter K Gregersen
P2860
P304
P356
10.1002/ART.39301
P577
2015-08-05T00:00:00Z