Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor-3-mediated regulation of endothelial nitric oxide synthase and mitogen-activated protein kinase activities.
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Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosisGlobal gene expression in neuroendocrine tumors from patients with the MEN1 syndromeDietary exposure to soy or whey proteins alters colonic global gene expression profiles during rat colon tumorigenesis.PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsThe expression of the phosphotyrosine phosphatase DEP-1/PTPeta dictates the responsivity of glioma cells to somatostatin inhibition of cell proliferationSomatostatin receptors 2 and 5 are preferentially expressed in proliferating endotheliumRegulation of NADPH-dependent Nitric Oxide and reactive oxygen species signalling in endothelial and melanoma cells by a photoactive NADPH analogue.Somatostatin and cancer: applying endocrinology to oncology.Transcriptome sequencing reveals differences between primary and secondary hair follicle-derived dermal papilla cells of the Cashmere goat (Capra hircus).ZAC1 and SSTR2 are downregulated in non-functioning pituitary adenomas but not in somatotropinomas.Long-time octreotide in an adolescent with severe haemorrhagic gastrointestinal vascular malformation.Somatostatin receptor biology in neuroendocrine and pituitary tumours: part 1--molecular pathways.Somatostatin receptor expression, tumour response, and quality of life in patients with advanced hepatocellular carcinoma treated with long-acting octreotide.Peptide receptor targeting in cancer: the somatostatin paradigm.Gastrin - active participant or bystander in gastric carcinogenesis?Presence of sst5TMD4, a truncated splice variant of the somatostatin receptor subtype 5, is associated to features of increased aggressiveness in pancreatic neuroendocrine tumors.Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats.Somatostatin analog octreotide LAR in gastro-entero-pancreatic tumors.Somatostatin and somatostatin receptors: implications for neoplastic growth and cancer biology.Somatostatin analogs for the treatment of neuroendocrine tumors.Somatostatin receptors in non-neuroendocrine malignancies: the potential role of somatostatin analogs in solid tumors.Investigational drugs targeting somatostatin receptors for treatment of acromegaly and neuroendocrine tumors.The expanding role of somatostatin analogs in gastroenteropancreatic and lung neuroendocrine tumors.PSG9 promotes angiogenesis by stimulating VEGFA production and is associated with poor prognosis in hepatocellular carcinoma.Current and future medical treatments for patients with acromegaly.Exploiting cancer's phenotypic guise against itself: targeting ectopically expressed peptide G-protein coupled receptors for lung cancer therapy.Effects of somatostatin and octreotide on the interactions between neoplastic gastroenteropancreatic endocrine cells and endothelial cells: a comparison between in vitro and in vivo properties.Inhibitory activity of the peptides derived from buffalo prolactin on angiogenesis.Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist.Regulation of neuronal nitric-oxide synthase activity by somatostatin analogs following SST5 somatostatin receptor activation.Diamine Derivatives as Novel Small-Molecule, Potent, and Subtype-Selective Somatostatin SST3 Receptor Agonists.Somatostatin inhibits colon cancer cell growth through cyclooxygenase-2 downregulation.Antiproliferative effect of somatostatin analogs in gastroenteropancreatic neuroendocrine tumors.Inhibition of tumor promoting signals by activation of SSTR2 and opioid receptors in human breast cancer cells.Immunohistochemical expression of pituitary tumor transforming gene (PTTG) in pituitary adenomas: a correlative study of tumor subtypes.Somatostatin receptors differentially affect spontaneous epileptiform activity in mouse hippocampal slices.Somatostatin receptor expression in adrenocortical tumors and effect of a new somatostatin analog SOM230 on hormone secretion in vitro and in ex vivo adrenal cells.Intimal hyperplasia in rats after subcutaneous injection of a somatostatin analog.Complete response after treatment with a somatostatin analogue in an adult patient with recurrent medulloblastoma.Differential efficacy of SSTR1, -2, and -5 agonists in the inhibition of C6 glioma growth in nude mice.
P2860
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P2860
Somatostatin inhibits tumor angiogenesis and growth via somatostatin receptor-3-mediated regulation of endothelial nitric oxide synthase and mitogen-activated protein kinase activities.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Somatostatin inhibits tumor an ...... ted protein kinase activities.
@en
type
label
Somatostatin inhibits tumor an ...... ted protein kinase activities.
@en
prefLabel
Somatostatin inhibits tumor an ...... ted protein kinase activities.
@en
P2093
P50
P356
P1433
P1476
Somatostatin inhibits tumor an ...... ated protein kinase activities
@en
P2093
P304
P356
10.1210/EN.2002-220949
P407
P50
P577
2003-04-01T00:00:00Z