Streptococcal cysteine proteinase releases kinins: a virulence mechanism.
about
Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: An integrin-binding cysteine proteaseUltrahigh and High Resolution Structures and Mutational Analysis of Monomeric Streptococcus pyogenes SpeB Reveal a Functional Role for the Glycine-rich C-terminal LoopEndoS, a novel secreted protein from Streptococcus pyogenes with endoglycosidase activity on human IgGPathogenesis of group A streptococcal infectionsIdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G.Uptake and intracellular transportation of a bacterial surface protein in lymphoid cells.alpha2-Macroglobulin-proteinase complexes protect Streptococcus pyogenes from killing by the antimicrobial peptide LL-37.A possible alternative mechanism of kinin generation in vivo by cathepsin L.EndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activitySpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.Genetic inactivation of an extracellular cysteine protease (SpeB) expressed by Streptococcus pyogenes decreases resistance to phagocytosis and dissemination to organsEffect of group A streptococcal cysteine protease on invasion of epithelial cells.Opsonic antibodies to the surface M protein of group A streptococci in pooled normal immunoglobulins (IVIG): potential impact on the clinical efficacy of IVIG therapy for severe invasive group A streptococcal infections.The M protein is dispensable for maturation of streptococcal cysteine protease SpeB.A role for trigger factor and an rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes.The rgg gene of Streptococcus pyogenes NZ131 positively influences extracellular SPE B production.Group A Streptococcus induces apoptosis in human epithelial cells.Absence of SpeB production in virulent large capsular forms of group A streptococcal strain 64Streptococcal erythrogenic toxin B abrogates fibronectin-dependent internalization of Streptococcus pyogenes by cultured mammalian cellsReplacement of histidine 340 with alanine inactivates the group A Streptococcus extracellular cysteine protease virulence factorInverse relation between disease severity and expression of the streptococcal cysteine protease, SpeB, among clonal M1T1 isolates recovered from invasive group A streptococcal infection casesIdentification of a novel maturation mechanism and restricted substrate specificity for the SspB cysteine protease of Staphylococcus aureus.From transcription to activation: how group A streptococcus, the flesh-eating pathogen, regulates SpeB cysteine protease production.Cysteine proteinase SpeB from Streptococcus pyogenes - a potent modifier of immunologically important host and bacterial proteins.Protease-armed bacteria in the skin.The contribution of group A streptococcal virulence determinants to the pathogenesis of sepsis.The effect of environmental conditions on expression of Bacteroides fragilis and Bacteroides thetaiotaomicron C10 protease genes.Adsorption of components of the plasma kinin-forming system on the surface of Porphyromonas gingivalis involves gingipains as the major docking platforms.Determining antibody-binding site of streptococcal pyrogenic exotoxin B to protect mice from group a streptococcus infectionProteolysis and its regulation at the surface of Streptococcus pyogenes.Kininogens coordinate adaptive immunity through the proteolytic release of bradykinin, an endogenous danger signal driving dendritic cell maturation.Bacterial protease inhibitors.Streptococcus pyogenes c-di-AMP phosphodiesterase, GdpP, influences SpeB processing and virulenceExtracellular enzymes with immunomodulating activities: variations on a theme in Streptococcus pyogenesActivation of the kallikrein-kinin system and release of new kinins through alternative cleavage of kininogens by microbial and human cell proteinases.Necrotizing fasciitis: pathogenesis and treatment.Induction of vascular leakage through release of bradykinin and a novel kinin by cysteine proteinases from Staphylococcus aureus.Degradation of complement 3 by streptococcal pyrogenic exotoxin B inhibits complement activation and neutrophil opsonophagocytosis.Humoral innate immune response and disease.Kininogenase activity by the major cysteinyl proteinase (cruzipain) from Trypanosoma cruzi.
P2860
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P2860
Streptococcal cysteine proteinase releases kinins: a virulence mechanism.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Streptococcal cysteine proteinase releases kinins: a virulence mechanism.
@en
type
label
Streptococcal cysteine proteinase releases kinins: a virulence mechanism.
@en
prefLabel
Streptococcal cysteine proteinase releases kinins: a virulence mechanism.
@en
P2860
P356
P1476
Streptococcal cysteine proteinase releases kinins: a virulence mechanism.
@en
P2093
P2860
P304
P356
10.1084/JEM.184.2.665
P407
P577
1996-08-01T00:00:00Z