The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein.
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Vapor of volatile oils from Litsea cubeba seed induces apoptosis and causes cell cycle arrest in lung cancer cellsNIR is a novel INHAT repressor that modulates the transcriptional activity of p53.The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexesMyosin VI is a mediator of the p53-dependent cell survival pathway.RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcriptPhysical interaction and mutual transrepression between CCAAT/enhancer-binding protein beta and the p53 tumor suppressorThe C terminus of p53 family proteins is a cell fate determinantVpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tailStructural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylationMultivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damageRegulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53Structure and apoptotic function of p73Prolyl 4-hydroxylation regulates Argonaute 2 stabilityGPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent mannerInterferon-inducible protein 16: insight into the interaction with tumor suppressor p53Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cellsDeltaNp73 modulates nerve growth factor-mediated neuronal differentiation through repression of TrkAp53 induces distinct epigenetic states at its direct target promoters.The role of p300 histone acetyltransferase in UV-induced histone modifications and MMP-1 gene transcriptionTwo distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylationDEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence.Myosin VI is differentially regulated by DNA damage in p53- and cell type-dependent mannersDNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.DeltaNp63, a target of DEC1 and histone deacetylase 2, modulates the efficacy of histone deacetylase inhibitors in growth suppression and keratinocyte differentiationInvolvement of S100A14 protein in cell invasion by affecting expression and function of matrix metalloproteinase (MMP)-2 via p53-dependent transcriptional regulationHistone deacetylase inhibitors suppress mutant p53 transcription via histone deacetylase 8.TP53 codon 72 Arg/Arg polymorphism is associated with a higher risk for inflammatory bowel disease development.p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells.p53 N-terminal phosphorylation: a defining layer of complex regulationMouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo.Hypoxic adaptation engages the CBP/CREST-induced coactivator complex of Creb-HIF-1α in transactivating murine neuroblastic glucose transporter.Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity.ID1, inhibitor of differentiation/DNA binding, is an effector of the p53-dependent DNA damage response pathway.Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutationsInduction of PPM1D following DNA-damaging treatments through a conserved p53 response element coincides with a shift in the use of transcription initiation sites.Dysfunctional telomeres induce p53-dependent and independent apoptosis to compromise cellular proliferation and inhibit tumor formation.Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation.PRMT5 is required for cell-cycle progression and p53 tumor suppressor function.Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway.
P2860
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P2860
The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The activation domains, the pr ...... ith p300/CREB-binding protein.
@en
type
label
The activation domains, the pr ...... ith p300/CREB-binding protein.
@en
prefLabel
The activation domains, the pr ...... ith p300/CREB-binding protein.
@en
P2860
P356
P1476
The activation domains, the pr ...... with p300/CREB-binding protein
@en
P2093
P2860
P304
17557-17565
P356
10.1074/JBC.M210696200
P407
P50
P577
2003-02-27T00:00:00Z