VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model.

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Targeting Adenosine Receptors for the Treatment of Cardiac Fibrosis Purinergic Signalling: Therapeutic Developments.Adenosine Receptors As Drug Targets for Treatment of Pulmonary Arterial Hypertension.Biased signalling: from simple switches to allosteric microprocessors.

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VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model.

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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VCP746, a novel A1 adenosine r ...... eonatal cardiac myocyte model.

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VCP746, a novel A1 adenosine r ...... eonatal cardiac myocyte model.

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VCP746, a novel A1 adenosine r ...... eonatal cardiac myocyte model.

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P1476

VCP746, a novel A1 adenosine r ...... neonatal cardiac myocyte model

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Bing H Wang

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Chung H Chuo

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Henry Krum

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Lauren T May

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Paul J White

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Inhibitory regulation of hypertrophy by endogenous atrial natriuretic peptide in cultured cardiac myocytes

Inhibition of phenylephrine-induced cardiomyocyte hypertrophy by activation of multiple adenosine receptor subtypes

Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.

Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor.

Left ventricular remodeling after myocardial infarction: pathophysiology and therapy.

Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant?

Heart failure therapy at a crossroad: are there limits to the neurohormonal model?

Myofibrillar remodeling in cardiac hypertrophy, heart failure and cardiomyopathies.

Return to the fetal gene program: a suggested metabolic link to gene expression in the heart.

Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist

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976-982

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scholarly article

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10.1111/1440-1681.12616

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P478

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Arthur Christopoulos

Peter J. Scammells

Shane M Devine

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2016-10-01T00:00:00Z

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27377874

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VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model.

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P2860

P2860

VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model.

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