Relevance of the proximal domain in the amino-terminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor.
about
Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating.Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a-go-go-related gene (hERG) potassium channelCytoplasmic domains and voltage-dependent potassium channel gating.Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator.Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits.Effects of TRH on heteromeric rat erg1a/1b K+ channels are dominated by the rerg1b subunit.Specificity of TRH receptor coupling to G-proteins for regulation of ERG K+ channels in GH3 rat anterior pituitary cells.Interactions between the N-terminal tail and the gating machinery of hERG K⁺ channels both in closed and open/inactive states.Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels.
P2860
Q30474096-B762E413-C3C2-4862-8FBC-AC9A3897F7AAQ34998277-33D5E167-B23C-49F3-A9CA-FC9BC885B2F3Q37999317-694EB4E1-8617-4FE6-982E-9F5B3FDEB438Q39911527-16E2AFB9-5934-4B90-8F35-9EC0BFDD9D1EQ40158533-E10C1694-D608-4A4B-93AC-C1C795F121AEQ40341709-DAA82B14-615C-40AB-9647-DCFB478C557CQ40419988-DADB2B5E-4CAE-4AB5-9A1F-8A6E7A1B7A1BQ42683368-20E4C2FB-28E7-42D3-B90A-71ED5BE840F3Q43205719-187CF495-7AAB-4243-A851-F7526501A860Q48630181-3E2A661A-CE41-4EE1-AD60-EEE727B57444
P2860
Relevance of the proximal domain in the amino-terminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Relevance of the proximal doma ...... se C-coupled hormone receptor.
@en
type
label
Relevance of the proximal doma ...... se C-coupled hormone receptor.
@en
prefLabel
Relevance of the proximal doma ...... se C-coupled hormone receptor.
@en
P2093
P2860
P1433
P1476
Relevance of the proximal doma ...... se C-coupled hormone receptor.
@en
P2093
Cristina G Viloria
David Gómez-Varela
Diego G Manso
Francisco Barros
Pablo Miranda
Pilar de la Peña
Silvia G Dupuy
Teresa Giráldez
P2860
P304
P356
10.1016/S0014-5793(02)03888-7
P407
P577
2003-01-01T00:00:00Z