The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).
about
Neuroprotective effects of physical activity on the brain: a closer look at trophic factor signalingPeroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cellsMultiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activationVEGF stimulation of mitochondrial biogenesis: requirement of AKT3 kinaseKaempferol is an estrogen-related receptor alpha and gamma inverse agonistPGC-1 coactivators: inducible regulators of energy metabolism in health and diseaseMitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exerciseEstrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscleErralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscleThe estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesisRegulation of hepatic ApoC3 expression by PGC-1β mediates hypolipidemic effect of nicotinic acidReduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alphaSCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysisOrphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesisRNAi technology and its use in studying the function of nuclear receptors and coregulators.Role of Energy Metabolism in the Brown Fat Gene ProgramCommunication between the ERRalpha homodimer interface and the PGC-1alpha binding surface via the helix 8-9 loopEvidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alphaAlternate day fasting impacts the brain insulin-signaling pathway of young adult male C57BL/6 miceCharacterization of a novel small molecule subtype specific estrogen-related receptor alpha antagonist in MCF-7 breast cancer cellsPGC-1alpha coactivates estrogen-related receptor-alpha to induce the expression of glucokinaseFasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alphaHic-5 regulates an epithelial program mediated by PPARgammaIRF4 is a key thermogenic transcriptional partner of PGC-1αMolecular mechanisms for mitochondrial adaptation to exercise training in skeletal muscle.Transcriptional co-expression and co-regulation of genes coding for components of the oxidative phosphorylation system.Electric pulse stimulation of cultured murine muscle cells reproduces gene expression changes of trained mouse muscleBile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor αEstrogen receptor-related receptor alpha mediates up-regulation of aromatase expression by prostaglandin E2 in prostate stromal cellsPhosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif.Physiological genomics identifies estrogen-related receptor alpha as a regulator of renal sodium and potassium homeostasis and the renin-angiotensin pathway.Nuclear receptors, mitochondria and lipid metabolismEstrogen-related receptor alpha 1 up-regulates endothelial nitric oxide synthase expression.Mitochondrial Effects of PGC-1alpha Silencing in MPP+ Treated Human SH-SY5Y Neuroblastoma Cells.Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in cultured myotubes.Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle.The role of PGC-1 coactivators in aging skeletal muscle and heart.Activation of nuclear receptor coactivator PGC-1alpha by arginine methylationRole of Esrrg in the fibrate-mediated regulation of lipid metabolism genes in human ApoA-I transgenic miceThe estrogen-related receptor α inverse agonist XCT 790 is a nanomolar mitochondrial uncoupler
P2860
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P2860
The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The transcriptional coactivato ...... ted receptor alpha (ERRalpha).
@en
type
label
The transcriptional coactivato ...... ted receptor alpha (ERRalpha).
@en
prefLabel
The transcriptional coactivato ...... ted receptor alpha (ERRalpha).
@en
P2093
P356
P1476
The transcriptional coactivato ...... ted receptor alpha (ERRalpha).
@en
P2093
Anastasia Kralli
Darko Knutti
Kathrin Brogli
Sylvia N Schreiber
Thomas Uhlmann
P304
P356
10.1074/JBC.M212923200
P407
P577
2003-01-08T00:00:00Z