The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.
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An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory PathogensIntegrin α9β1 in airway smooth muscle suppresses exaggerated airway narrowing.Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33.TGF-β activation and function in immunity.Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbationsMast cell proteases as pharmacological targetsMatrix protein CCN1 induced by bacterial DNA and CpG ODN limits lung inflammation and contributes to innate immune homeostasisMitochondrial-targeted antioxidant therapy decreases transforming growth factor-β-mediated collagen production in a murine asthma modelMaturation of mast cell progenitors to mucosal mast cells during allergic pulmonary inflammation in miceAlternaria induces STAT6-dependent acute airway eosinophilia and epithelial FIZZ1 expression that promotes airway fibrosis and epithelial thickness.High IFN-γ and low SLPI mark severe asthma in mice and humans.Genome-wide transcriptional profiling reveals connective tissue mast cell accumulation in bronchopulmonary dysplasia.Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus.Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction.Airway smooth muscle in the pathophysiology and treatment of asthma.α8β1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism.Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma.The contractile lability of smooth muscle in asthmatic airway hyperresponsiveness.Control of local immunity by airway epithelial cells.Claudin-18 deficiency is associated with airway epithelial barrier dysfunction and asthma.Transforming Growth Factor β1 Function in Airway Remodeling and Hyperresponsiveness. The Missing Link?Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1.Bifidobacterium breve and Lactobacillus rhamnosus treatment is as effective as budesonide at reducing inflammation in a murine model for chronic asthmaIQGAP1-dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction.Blocking immunosuppression by human Tregs in vivo with antibodies targeting integrin αVβ8.Oral administration of Clostridium butyricum CGMCC0313-1 reduces ovalbumin-induced allergic airway inflammation in mice.Airway brushing as a new experimental methodology to detect airway gene expression signatures in mouse lung squamous cell carcinoma.Pathology of asthma
P2860
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P2860
The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The αvβ6 integrin modulates ai ...... ng intraepithelial mast cells.
@en
type
label
The αvβ6 integrin modulates ai ...... ng intraepithelial mast cells.
@en
prefLabel
The αvβ6 integrin modulates ai ...... ng intraepithelial mast cells.
@en
P2093
P2860
P356
P1476
The αvβ6 integrin modulates ai ...... ing intraepithelial mast cells
@en
P2093
Aparna Sundaram
Dean Sheppard
George H Caughey
Katherine Huang
Kotaro Sugimoto
Magnus Abrink
Makoto Kudo
Wilfred W Raymond
Xiaozhu Huang
Xin Bernstein
P2860
P304
P356
10.1172/JCI58815
P407
P50
P577
2012-01-09T00:00:00Z