Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity.
about
Androgen regulation of the human FERM domain encoding gene EHM2 in a cell model of steroid-induced differentiationPhosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrinInactivation of aPKClambda reveals a context dependent allocation of cell lineages in preimplantation mouse embryosOrganizing the cell cortex: the role of ERM proteinsBeta adrenergic overstimulation impaired vascular contractility via actin-cytoskeleton disorganization in rabbit cerebral arteryMoesin functionality in hypothermic liver preservation injuryThe NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.Rho1 has multiple functions in Drosophila wing planar polarity.Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane.Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells.The Nck-interacting kinase phosphorylates ERM proteins for formation of lamellipodium by growth factors.Moesin and its activating kinase Slik are required for cortical stability and microtubule organization in mitotic cellsCCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformationsEzrin-mediated apical integrity is required for intestinal homeostasis.Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient.Parvin overexpression uncovers tissue-specific genetic pathways and disrupts F-actin to induce apoptosis in the developing epithelia in DrosophilaGene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targetsKinetic and mechanical analysis of live tube morphogenesis.Sds22, a PP1 phosphatase regulatory subunit, regulates epithelial cell polarity and shape [Sds22 in epithelial morphology].Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism.Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice.Sip1, the Drosophila orthologue of EBP50/NHERF1, functions with the sterile 20 family kinase Slik to regulate Moesin activity.Rho1 regulates apoptosis via activation of the JNK signaling pathway at the plasma membrane.Src-dependent ezrin phosphorylation in adhesion-mediated signalingThe Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor.Control of axon-axon attraction by Semaphorin reverse signaling.Akt2 phosphorylates ezrin to trigger NHE3 translocation and activationOverlapping roles of Drosophila Drak and Rok kinases in epithelial tissue morphogenesisWASp is required for the correct temporal morphogenesis of rhabdomere microvilli.Epithelial junctions maintain tissue architecture by directing planar spindle orientation.Role of moesin in renal fibrosis.A Drosophila model of multiple endocrine neoplasia type 2.Deleted in Colorectal Cancer (DCC) pathfinding: axon guidance gene finally turned tumor suppressor.New components of Drosophila leg development identified through genome wide association studiesEmerging role for ERM proteins in cell adhesion and migration.Actin capping protein alpha maintains vestigial-expressing cells within the Drosophila wing disc epitheliumProteomic changes during B cell maturation: 2D-DIGE approach.Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinasesSds22/PP1 links epithelial integrity and tumor suppression via regulation of myosin II and JNK signaling
P2860
Q24296691-6893DB0F-110F-4204-9D00-5A9FDDE5795EQ24676944-042BC507-0C50-40A2-ADAA-15991A395B4AQ27341954-CAD027DF-76B4-42F0-88C4-9C8B809B94A0Q28277373-55C8F375-83E6-4484-8D06-6B22BA66CC93Q28482409-6C50188B-FAEF-48A9-AD44-54B119E3202AQ30371568-63A9CBEF-92F2-4AD8-B904-9D63A85F3188Q30429717-38728D3C-448E-4AC4-A766-DCD9AA60206AQ30434910-E939C765-0526-4B8F-8491-6B7D0DA4B4DDQ30443407-5B7FAE95-44DC-4C83-A8DF-7BA15DFA0593Q30443779-1DE5386D-2808-44F0-9A00-41A608544106Q30477995-F7C48D6E-872B-471C-A0F1-48D6CDB235FEQ30481432-B721FA6B-56D2-4C71-A9E1-DD58AA02ACEDQ30495754-EECF64D8-70F1-4F0E-8A5D-DC8AF00B4C4DQ30502773-9E283100-CB99-4FBB-A39B-337BCB984203Q30620016-C2A81CC7-8904-4A0D-9864-6B98F6CDF439Q31105316-030BCD1B-AC57-45E5-A6F9-811872ED9481Q33212086-0576B514-B1D4-4EFF-B742-7457B7800C12Q33371897-98F67820-1725-42EB-AE20-BF0D120A5EA0Q33410690-4C5B3BC5-D2C1-44AB-871B-14B3909BC3F0Q33591167-F145CB0A-ABAE-476F-9A3D-F212021E50E2Q33678939-B87388C6-8568-4107-8309-C07E4CCFB705Q33748611-A65C66DC-1135-41E0-B277-1CA3471750A0Q33799194-080531C2-D42F-4B8C-9E26-C003BB6148C6Q33914506-B9FAE4BD-C28C-4332-A902-E11DF859A7EAQ33932269-048CC7BA-9774-4F81-801C-0CB019C6448BQ34025456-6E36B07D-F463-45B2-A1FB-88B4FF73A06BQ34049636-ECB920EE-40A0-45FE-9D96-93B71AE3FF02Q34063807-1CA580C3-FDA6-4C42-B2B8-D362D8ED3550Q34292762-D9E27830-67A0-417C-A669-04616443E2EBQ34358882-71F36E2A-D1A6-48DE-B13F-AA734CB42513Q34535574-2D875832-97CA-4F05-9E69-13104CD3D09AQ34589821-78D48DB2-DF04-47AD-BE0F-6D89DB41BFEEQ34641317-D27F9A35-CEC3-4144-9A1A-3D680E67DA85Q34656362-1287EF55-39F7-4305-B54C-698FE1EAA2A7Q34891331-990576AC-2FBD-467E-8881-1E8C26D91CB6Q34984873-481A57B5-5D1E-4618-B5EC-280EB74E55E9Q35035757-11FCFA16-7B41-4312-896F-570705746999Q35060075-B804961F-A5C6-4BCE-AAB4-A10D9D01DBAEQ35067915-4F84CA41-7B1A-4CD0-9291-A0C910BE5A99Q35120368-54C33918-5F0B-4AA8-9365-5264D2162400
P2860
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity.
@en
type
label
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity.
@en
prefLabel
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity.
@en
P2093
P356
P1433
P1476
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity.
@en
P2093
Nicole K Noren
Olga Speck
Richard G Fehon
Rima M Kulikauskas
Sarah C Hughes
P2888
P356
10.1038/NATURE01295
P407
P577
2003-01-01T00:00:00Z
P5875
P6179
1030620117