A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes.
about
Chimeric Antigen Receptor- and TCR-Modified T Cells Enter Main Street and Wall StreetT cell stimulator cells, an efficient and versatile cellular system to assess the role of costimulatory ligands in the activation of human T cells.A panel of artificial APCs expressing prevalent HLA alleles permits generation of cytotoxic T cells specific for both dominant and subdominant viral epitopes for adoptive therapy.Adoptive-cell-transfer therapy for the treatment of patients with cancerAugmented lymphocyte expansion from solid tumors with engineered cells for costimulatory enhancementTCR affinity and specificity requirements for human regulatory T-cell functionPreparing clinical grade Ag-specific T cells for adoptive immunotherapy trials.Biomimetic delivery with micro- and nanoparticlesUmbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cellsCD28 costimulation is essential for human T regulatory expansion and functionCD62L+ NKT cells have prolonged persistence and antitumor activity in vivo.Monosomy 1p36 uncovers a role for OX40 in survival of activated CD4+ T cells.4-1BB is superior to CD28 costimulation for generating CD8+ cytotoxic lymphocytes for adoptive immunotherapy.PD-1 signaling in primary T cellsEngineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules.Plasma levels of soluble programmed death ligand-1 may be associated with overall survival in nonsmall cell lung cancer patients receiving thoracic radiotherapy.Adoptive immunotherapy for cancer.Adoptive immunotherapy for cancer or viruses.Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytesSite-specific host gene modification by zinc finger nucleases: pointing the way to drug free control of HIV-1?Performance-enhancing drugs: design and production of redirected chimeric antigen receptor (CAR) T cells.Current status of chimeric antigen receptor therapy for haematological malignancies.HIV integration site distributions in resting and activated CD4+ T cells infected in culture.Efficient priming and expansion of antigen-specific CD8+ T cells by a novel cell-based artificial APC.Amino-terminal extended peptide single-chain trimers are potent synthetic agonists for memory human CD8+ T cells.Transient stimulation expands superior antitumor T cells for adoptive therapy.Improved Expansion and In Vivo Function of Patient T Cells by a Serum-free Medium.Enhanced MHC class I and costimulatory molecules on B16F10 cells by Ganoderma lucidum polysaccharides.
P2860
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P2860
A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
A cell-based artificial antige ...... m growth of CD4 T lymphocytes.
@en
type
label
A cell-based artificial antige ...... m growth of CD4 T lymphocytes.
@en
prefLabel
A cell-based artificial antige ...... m growth of CD4 T lymphocytes.
@en
P2093
P356
P1433
P1476
A cell-based artificial antige ...... m growth of CD4 T lymphocytes.
@en
P2093
Anna K Thomas
Carl H June
Waleed S Shalaby
P304
P356
10.1006/CLIM.2002.5277
P577
2002-12-01T00:00:00Z