Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
about
Extreme growth factor signalling can promote oestrogen receptor-alpha loss: therapeutic implications in breast cancerCrystal structures of the fungal pathogenAspergillus fumigatusprotein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug designRasfonin, a novel 2-pyrone derivative, induces ras-mutated Panc-1 pancreatic tumor cell death in nude mice.Inhibition of transforming growth factor-beta signaling in normal lung epithelial cells confers resistance to ionizing radiation.The role of TGF-beta in epithelial malignancy and its relevance to the pathogenesis of oral cancer (part II).Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.Antisense MDM2 enhances E2F1-induced apoptosis and the combination sensitizes androgen-sensitive [corrected] and androgen-insensitive [corrected] prostate cancer cells to radiation.Concomitant underexpression of TGFBR2 and overexpression of hTERT are associated with poor prognosis in cervical cancer.Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer's Disease.Absence of K-Ras Reduces Proliferation and Migration But Increases Extracellular Matrix Synthesis in Fibroblasts.GAM/ZFp/ZNF512B is central to a gene sensor circuitry involving cell-cycle regulators, TGF{beta} effectors, Drosha and microRNAs with opposite oncogenic potentials.Role of Radiation-induced TGF-beta Signaling in Cancer Therapy.H-Ras isoform modulates extracellular matrix synthesis, proliferation, and migration in fibroblasts.
P2860
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P2860
Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Farnesyltransferase inhibitor ...... c cancer cell line MIA PaCa-2.
@en
type
label
Farnesyltransferase inhibitor ...... c cancer cell line MIA PaCa-2.
@en
prefLabel
Farnesyltransferase inhibitor ...... c cancer cell line MIA PaCa-2.
@en
P2093
P2860
P356
P1433
P1476
Farnesyltransferase inhibitor ...... c cancer cell line MIA PaCa-2.
@en
P2093
Damodaran Chendil
George Hartman
Lee K Chatfield
Mansoor M Ahmed
Mohammed Mohiuddin
Mohammed S Inayat
Rachael A Alcock
Swatee Dey
Vincent S Gallicchio
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205948
P407
P577
2002-11-01T00:00:00Z
P5875
P6179
1001085657