Exogenous Nef protein activates NF-kappa B, AP-1, and c-Jun N-terminal kinase and stimulates HIV transcription in promonocytic cells. Role in AIDS pathogenesis.
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IKK2 inhibitor alleviates kidney and wasting diseases in a murine model of human AIDSRecent advances on viral manipulation of NF-κB signaling pathwayThe roles of HIV-1 proteins and antiretroviral drug therapy in HIV-1-associated endothelial dysfunctionModulation of NF-κB signalling by microbial pathogensMolecular interactions of human immunodeficiency virus type 1 with primary human oral keratinocytes.A novel HIV-1-encoded microRNA enhances its viral replication by targeting the TATA box region.Cellular activation and intracellular HCV load in peripheral blood monocytes isolated from HCV monoinfected and HIV-HCV coinfected patientsTargeting TNF and TNF Receptor Pathway in HIV-1 Infection: from Immune Activation to Viral ReservoirsShort communication: Methamphetamine treatment increases in vitro and in vivo HIV replication.Genetic characterization of HIV type 1 Nef-induced vesicle secretionExogenous Nef is an inhibitor of Mycobacterium tuberculosis-induced tumor necrosis factor-alpha production and macrophage apoptosis.Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineageDefective IL-17- and IL-22-dependent mucosal host response to Candida albicans determines susceptibility to oral candidiasis in mice expressing the HIV-1 transgene.Imbalance between HAT and HDAC activities in the PBMCs of patients with ankylosing spondylitis or rheumatoid arthritis and influence of HDAC inhibitors on TNF alpha production.Nef inhibits glucose uptake in adipocytes and contributes to insulin resistance in human immunodeficiency virus type I infection.Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis.Secretion modification region-derived peptide disrupts HIV-1 Nef's interaction with mortalin and blocks virus and Nef exosome release.Differential signaling mechanism for HIV-1 Nef-mediated production of IL-6 and IL-8 in human astrocytes.Inhibition of ER stress-mediated apoptosis in macrophages by nuclear-cytoplasmic relocalization of eEF1A by the HIV-1 Nef protein.Viral infection: an evolving insight into the signal transduction pathways responsible for the innate immune responseValidation of a novel secretion modification region (SMR) of HIV-1 Nef using cohort sequence analysis and molecular modeling.Human and simian immunodeficiency viruses deregulate early hematopoiesis through a Nef/PPARgamma/STAT5 signaling pathway in macaquesTuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line.TNF and TNF receptor superfamily members in HIV infection: new cellular targets for therapy?HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef proteinHIV-1 Nef induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors.Inhibition of Kaposi's sarcoma-associated herpesvirus lytic replication by HIV-1 Nef and cellular microRNA hsa-miR-1258.Macrophage signaling in HIV-1 infection.Clostridium difficile infection in patients with HIV/AIDS.Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 NefInteractions between Nef and AIP1 proliferate multivesicular bodies and facilitate egress of HIV-1.Synthetic Vpr protein activates activator protein-1, c-Jun N-terminal kinase, and NF-kappaB and stimulates HIV-1 transcription in promonocytic cells and primary macrophages.Interaction between Nef and INI1/SMARCB1 augments replicability of HIV-1 in resting human peripheral blood mononuclear cells.Incorporating the type and direction information in predicting novel regulatory interactions between HIV-1 and human proteins using a biclustering approach.HIV-1 Nef inhibits lipopolysaccharide-induced IL-12p40 expression by inhibiting JNK-activated NFkappaB in human monocytic cells.The HIV-1 Nef protein interacts with two components of the 40S small ribosomal subunit, the RPS10 protein and the 18S rRNA.Acting locally: innate mucosal immunity in resistance to HIV-1 infection in Kenyan commercial sex workers.HIV-1 Nef regulates the release of superoxide anions from human macrophages.Human immunodeficiency virus-1 Nef protein interacts with Tat and enhances HIV-1 gene expression.
P2860
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P2860
Exogenous Nef protein activates NF-kappa B, AP-1, and c-Jun N-terminal kinase and stimulates HIV transcription in promonocytic cells. Role in AIDS pathogenesis.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Exogenous Nef protein activate ...... ls. Role in AIDS pathogenesis.
@en
type
label
Exogenous Nef protein activate ...... ls. Role in AIDS pathogenesis.
@en
prefLabel
Exogenous Nef protein activate ...... ls. Role in AIDS pathogenesis.
@en
P2093
P50
P356
P1476
Exogenous Nef protein activate ...... ls. Role in AIDS pathogenesis.
@en
P2093
Anne-Zélie Decrion
Audrey Varin
Bharat B Aggarwal
Georges Herbein
Sunil K Manna
Vincent Quivy
P304
P356
10.1074/JBC.M209622200
P407
P577
2002-11-04T00:00:00Z