The jaagsiekte sheep retrovirus envelope gene induces transformation of the avian fibroblast cell line DF-1 but does not require a conserved SH2 binding domain.
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Role of virus receptor Hyal2 in oncogenic transformation of rodent fibroblasts by sheep betaretrovirus env proteinsTransformation and scattering activities of the receptor tyrosine kinase RON/Stk in rodent fibroblasts and lack of regulation by the jaagsiekte sheep retrovirus receptor, Hyal2Expression of the jaagsiekte sheep retrovirus envelope glycoprotein is sufficient to induce lung tumors in sheepCoevolution of endogenous betaretroviruses of sheep and their hostFriendly viruses: the special relationship between endogenous retroviruses and their hostEndogenous retroviruses in trophoblast differentiation and placental developmentApplication of next generation sequencing in mammalian embryogenomics: lessons learned from endogenous betaretroviruses of sheepJaagsiekte sheep retrovirus transformation in Madin-Darby canine kidney epithelial cell three-dimensional culture.Lung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repairA human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasionFunctional interaction between Env oncogene from Jaagsiekte sheep retrovirus and tumor suppressor Sprouty2.Sheep retrovirus structural protein induces lung tumours"Ménage à Trois": the evolutionary interplay between JSRV, enJSRVs and domestic sheep.Transformation of rodent fibroblasts by the jaagsiekte sheep retrovirus envelope is receptor independent and does not require the surface domain.Putative phosphatidylinositol 3-kinase (PI3K) binding motifs in ovine betaretrovirus Env proteins are not essential for rodent fibroblast transformation and PI3K/Akt activationJaagsiekte sheep retrovirus detected in human lung cancer tissue arrays.Jaagsiekte sheep retrovirus biology and oncogenesis.Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRVCritical role of leucine-valine change in distinct low pH requirements for membrane fusion between two related retrovirus envelopes.Enhanced proliferation of primary rat type II pneumocytes by Jaagsiekte sheep retrovirus envelope protein.Role for a Zinc Finger Protein (Zfp111) in Transformation of 208F Rat Fibroblasts by Jaagsiekte Sheep Retrovirus Envelope Protein.Fusogenicity of Jaagsiekte sheep retrovirus envelope protein is dependent on low pH and is enhanced by cytoplasmic tail truncations.Oncogenic transformation by the jaagsiekte sheep retrovirus envelope protein.A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma.Analysis of integration sites of Jaagsiekte sheep retrovirus in ovine pulmonary adenocarcinoma.Enzootic nasal tumor virus envelope requires a very acidic pH for fusion activation and infection.Analysis of jaagsiekte sheep retrovirus (JSRV) envelope protein domains in transformation.Host species barriers to Jaagsiekte sheep retrovirus replication and carcinogenesis.Oncogenesis by retroviruses: old and new paradigms.Identification and mutational analysis of a Rej response element in Jaagsiekte sheep retrovirus RNA.Multiple domains of the Jaagsiekte sheep retrovirus envelope protein are required for transformation of rodent fibroblasts.Evidence against a role for jaagsiekte sheep retrovirus in human lung cancer.Transformation of madin-darby canine kidney epithelial cells by sheep retrovirus envelope proteins.Expression and characterization of a soluble, active form of the jaagsiekte sheep retrovirus receptor, Hyal2.Recent advances in the study of active endogenous retrovirus envelope glycoproteins in the mammalian placenta.Three-dimensional culture of an ovine pulmonary adenocarcinoma-derived cell line results in re-expression of surfactant proteins and Jaagsiekte sheep retrovirus.In vivo tumorigenesis by Jaagsiekte sheep retrovirus (JSRV) requires Y590 in Env TM, but not full-length orfX open reading frame.Transformation of mouse fibroblasts by Jaagsiekte sheep retrovirus envelope does not require phosphatidylinositol 3-kinase.Signal transduction pathways utilized by enzootic nasal tumor virus (ENTV-1) envelope protein in transformation of rat epithelial cells resemble those used by jaagsiekte sheep retrovirus.Comparison of LTR enhancer elements in sheep beta retroviruses: insights into the basis for tissue-specific expression.
P2860
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P2860
The jaagsiekte sheep retrovirus envelope gene induces transformation of the avian fibroblast cell line DF-1 but does not require a conserved SH2 binding domain.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The jaagsiekte sheep retroviru ...... conserved SH2 binding domain.
@en
type
label
The jaagsiekte sheep retroviru ...... conserved SH2 binding domain.
@en
prefLabel
The jaagsiekte sheep retroviru ...... conserved SH2 binding domain.
@en
P2093
P1476
The jaagsiekte sheep retroviru ...... conserved SH2 binding domain.
@en
P2093
James C DeMartini
Jonathan O Carlson
Kate J Sherrill
Matthew R Perrott
Sara M Crispell
Thomas E Allen
P304
P356
10.1099/0022-1317-83-11-2733
P407
P577
2002-11-01T00:00:00Z