A futile metabolic cycle activated in adipocytes by antidiabetic agents.
about
Cytosolic aspartate aminotransferase, a new partner in adipocyte glyceroneogenesis and an atypical target of thiazolidinedioneMoonlighting function of glycerol kinase causes systems-level changes in rat hepatoma cellsImplication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.Modulation of the transcriptional activity of peroxisome proliferator-activated receptor gamma by protein-protein interactions and post-translational modificationsStructure and non-essential function of glycerol kinase inPlasmodium falciparumblood stagesObesity is associated with macrophage accumulation in adipose tissuePPARγ as a therapeutic target to rescue mitochondrial function in neurological diseaseThe cell biology of fat expansionC13orf31 (FAMIN) is a central regulator of immunometabolic functionIdentification of a novel mitochondrial protein ("mitoNEET") cross-linked specifically by a thiazolidinedione photoprobe'Striking the Right Balance' in Targeting PPARgamma in the Metabolic Syndrome: Novel Insights from Human Genetic StudiesNutrigenomics of body weight regulation: a rationale for careful dissection of individual contributorsTranscriptomic and network component analysis of glycerol kinase in skeletal muscle using a mouse model of glycerol kinase deficiencyPPARalpha governs glycerol metabolismCorepressors selectively control the transcriptional activity of PPARgamma in adipocytesMetabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alphaExpression of glycerokinase in brown adipose tissue is stimulated by the sympathetic nervous systemPPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.Long-term ritonavir exposure increases fatty acid and glycerol recycling in 3T3-L1 adipocytes as compensatory mechanisms for increased triacylglycerol hydrolysis.Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase.Obesity and metabolic perturbations after loss of aquaporin 7, the adipose glycerol transporter.Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.Glycerol kinase deficiency alters expression of genes involved in lipid metabolism, carbohydrate metabolism, and insulin signaling.Global metabolic effects of glycerol kinase overexpression in rat hepatoma cells.Involvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor gamma activation in mice.Apelin-13 decreases lipid storage in hypertrophic adipocytes in vitro through the upregulation of AQP7 expression by the PI3K signaling pathwayTrans-10,cis-12 CLA increases adipocyte lipolysis and alters lipid droplet-associated proteins: role of mTOR and ERK signaling.Transcriptional targets in adipocyte biologyBone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes.Combined transcriptomic-(1)H NMR metabonomic study reveals that monoethylhexyl phthalate stimulates adipogenesis and glyceroneogenesis in human adipocytes.DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.RIP140 represses the "brown-in-white" adipocyte program including a futile cycle of triacylglycerol breakdown and synthesis.PPAR gamma and human metabolic diseasePhosphoenolpyruvate carboxykinase (Pck1) helps regulate the triglyceride/fatty acid cycle and development of insulin resistance in mice.Revisiting PPARγ as a target for the treatment of metabolic disordersFunction of phosphoenolpyruvate carboxykinase in mammary gland epithelial cells.Aquaglyceroporins serve as metabolic gateways in adiposity and insulin resistance control.PPARgamma and metabolism: insights from the study of human genetic variants.Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways.Mathematical modeling of the insulin signal transduction pathway for prediction of insulin sensitivity from expression data.
P2860
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P2860
A futile metabolic cycle activated in adipocytes by antidiabetic agents.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
A futile metabolic cycle activated in adipocytes by antidiabetic agents.
@en
type
label
A futile metabolic cycle activated in adipocytes by antidiabetic agents.
@en
prefLabel
A futile metabolic cycle activated in adipocytes by antidiabetic agents.
@en
P2093
P2860
P356
P1433
P1476
A futile metabolic cycle activated in adipocytes by antidiabetic agents.
@en
P2093
Christopher B Newgard
Claire M Steppan
Hong-Ping Guan
Mette Valentin Jensen
Mitchell A Lazar
P2860
P2888
P304
P356
10.1038/NM780
P407
P577
2002-09-23T00:00:00Z
P5875
P6179
1049032657