IRF3 mediates a TLR3/TLR4-specific antiviral gene program.
about
A large fraction of extragenic RNA pol II transcription sites overlap enhancersA new insight into hepatitis C vaccine developmentNuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signalingThe GRIP1:IRF3 interaction as a target for glucocorticoid receptor-mediated immunosuppressionHigh mobility group Box 1 inhibits human pulmonary artery endothelial cell migration via a Toll-like receptor 4- and interferon response factor 3-dependent mechanism(s)Viral apoptosis is induced by IRF-3-mediated activation of BaxNovel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivoThe DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune responseRegulation of antiviral responses by a direct and specific interaction between TRAF3 and CardifActivation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunityUnbiased reconstruction of a mammalian transcriptional network mediating pathogen responsesHistone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongationLPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIFMicroRNA-155 is induced during the macrophage inflammatory responseLPS induces CD40 gene expression through the activation of NF-kappaB and STAT-1alpha in macrophages and microgliaToll-like receptor downstream signaling.Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly(I:C) on the regulation of Toll-like receptors, adaptor proteins and inflammatory responseMolecular control of activation and priming in macrophagesImmunity to Pathogens Taught by Specialized Human Dendritic Cell SubsetsInsights into phagocytosis-coupled activation of pattern recognition receptors and inflammasomesModification by ubiquitin-like proteins: significance in apoptosis and autophagy pathwaysInfluenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I InterferonsNovel Role of Toll-Like Receptor 3 in Hepatitis C-Associated GlomerulonephritisWest Nile Virus-Induced Interferon Production Is Mediated by the Double-Stranded RNA-Dependent Protein Kinase PKRX-ray crystal structure of IRF-3 and its functional implicationsHERC5 is an IFN-induced HECT-type E3 protein ligase that mediates type I IFN-induced ISGylation of protein targetsThe role of Toll-like receptors in retinal ischemic diseasesDanger Signals and Graft-versus-host Disease: Current Understanding and Future PerspectivesSpace and time: New considerations about the relationship between Toll-like receptors (TLRs) and type I interferons (IFNs)Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANKTRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathwayTRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-betaDlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cellsTRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cellsTRIM35 negatively regulates TLR7- and TLR9-mediated type I interferon production by targeting IRF7High-resolution temporal response patterns to influenza vaccine reveal a distinct human plasma cell gene signatureEndothelial TNF receptor 2 induces IRF1 transcription factor-dependent interferon-β autocrine signaling to promote monocyte recruitment.The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.
P2860
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P2860
IRF3 mediates a TLR3/TLR4-specific antiviral gene program.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
IRF3 mediates a TLR3/TLR4-specific antiviral gene program.
@en
type
label
IRF3 mediates a TLR3/TLR4-specific antiviral gene program.
@en
prefLabel
IRF3 mediates a TLR3/TLR4-specific antiviral gene program.
@en
P2093
P1433
P1476
IRF3 mediates a TLR3/TLR4-specific antiviral gene program.
@en
P2093
Govinda Rao
Hajir Dadgostar
Margaret Haberland
Paul Dempsey
Ryan O'Connell
Sagar Vaidya
Sean Doyle
P304
P356
10.1016/S1074-7613(02)00390-4
P407
P577
2002-09-01T00:00:00Z