Tryptase activates the mitogen-activated protein kinase/activator protein-1 pathway in human peripheral blood eosinophils, causing cytokine production and release.
about
Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic processJab1, a novel protease-activated receptor-2 (PAR-2)-interacting protein, is involved in PAR-2-induced activation of activator protein-1Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRsHuman airway trypsin-like protease stimulates human bronchial fibroblast proliferation in a protease-activated receptor-2-dependent pathwayThrombin induced connective tissue growth factor expression in rat vascular smooth muscle cells via the PAR-1/JNK/AP-1 pathway.Expression of mast cell proteases correlates with mast cell maturation and angiogenesis during tumor progression.Development of testicular inflammation in the rat involves activation of proteinase-activated receptor-2.Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formationPreformed enzymes in mast cell granules and their potential role in allergic rhinitis.Extracellular proteases as targets for drug developmentTissue factor, blood coagulation, and beyond: an overview.Biochemical assessment of intracellular signal transduction pathways in eosinophils: implications for pharmacotherapy.Role of Allergen Source-Derived Proteases in Sensitization via Airway Epithelial Cells.Biology of mast cell tryptase. An inflammatory mediator.Activation of human colon mast cells through proteinase activated receptor-2.A 27 kDa cysteine protease secreted by newly excysted Paragonimus westermani metacercariae induces superoxide anion production and degranulation of human eosinophilsProteinases and signalling: pathophysiological and therapeutic implications via PARs and more.Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome.Protease-activated receptors and prostaglandins in inflammatory lung disease.Mast cells and eosinophils: the two key effector cells in allergic inflammation.Early regression of spermatogenesis in boars of an inbred Duroc strain caused by incident orchitis/epididymo-orchitis.Mast cells in asthma--state of the art.Alpha A-crystallin and alpha B-crystallin, newly identified interaction proteins of protease-activated receptor-2, rescue astrocytes from C2-ceramide- and staurosporine-induced cell death.Signal pathway of cytokines produced by reactive oxygen species generated from phorbol myristate acetate-stimulated HMC-1 cells.Bidirectional Mast Cell-Eosinophil Interactions in Inflammatory Disorders and Cancer.Beta-tryptase regulates IL-8 expression in airway smooth muscle cells by a PAR-2-independent mechanism.Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblastsIncreased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation.Interacting mast cells and eosinophils acquire an enhanced activation state in vitro.Signal transduction pathways in mast cell granule-mediated endothelial cell activation.Eosinophil major basic protein activates human cord blood mast cells primed with fibroblast membranes by integrin-β1.Mast cell tryptase activates peripheral blood eosinophils to release granule-associated enzymes.Expression and regulation of c-Jun N-terminal kinase (JNK) in endometrial cells in vivo and in vitro.Regenerative potential of human schneiderian membrane: progenitor cells and epithelial-mesenchymal transition.Activation of proteinase-activated receptor-2 in mesothelial cells induces pleural inflammation.Expression and secretion of CXCL8 (IL-8), release of tryptase and transcription of histidine decarboxylase mRNA by anti-IgE-activated human umbilical cord blood-derived cultured mast cells.Eotaxin selectively binds heparin. An interaction that protects eotaxin from proteolysis and potentiates chemotactic activity in vivo.beta-Tryptase up-regulates vascular endothelial growth factor expression via proteinase-activated receptor-2 and mitogen-activated protein kinase pathways in bone marrow stromal cells in acute myeloid leukemia.
P2860
Q24296718-5EDD7486-C731-427B-8578-86179982037EQ24300972-0109EE91-C5AB-4164-9D0F-9EBD520FECEBQ24318701-679628D7-6B77-4398-944D-CFF354D506D4Q28275097-3825A7C7-7AFB-4D95-BED4-32563C363B56Q33566993-C4C3719C-B846-461D-A869-98BF71EDC8E4Q34345203-57ED14B7-62EE-4251-8778-E2C3393D09A5Q34490290-EC840C90-57EC-4724-83C9-0C34F9F0C9D8Q35024817-3EC6C8B0-CFCF-479A-B0C5-88967A21659BQ35093804-9F94FBAE-1E25-465A-B055-567AF7C8C348Q35116202-E9E7621C-7BF7-42E7-8543-5C793842531FQ35222618-7EBE6BDC-2A74-4248-A3C2-2D14D875843BQ35743287-3CD2ED95-11F4-4506-BFC5-EB01E79A05C9Q35829828-9C2D413F-893F-47FE-A697-55BED98DAFF9Q36460904-529E24B0-1220-4E01-95ED-C692CDC730ADQ36496241-38FBA5A5-E651-4830-8A0C-F73BDD507FCDQ36868087-2F21DB08-E29F-4561-BB26-7FFAD8B17FD0Q37024500-0E8F2228-56F8-4AC0-8AE9-4AC7679395B0Q37253300-C09583F6-17CB-4A54-B8EA-0A021B60648BQ37273142-2A9BF14A-1AF7-4EF6-BCF7-774AD391CC8DQ37447476-F78E84C7-23F0-436C-B0B2-1D7F687A6BEEQ37480813-E2D9196B-48CF-4DF7-BED7-5B6E2ECAFF21Q37602089-2B4B4163-AA2E-4C96-BD88-058572DB2B86Q38633155-3D1B4BF6-3958-405F-8296-CF7F57E9D2AFQ39832639-23088CC7-CF69-42ED-A26A-B37FCDF9047FQ40387021-A58DE98B-1080-4C75-AB0C-FE709F126149Q41098587-1340B4EC-C15C-4EC5-B9D7-C225BDC22AECQ41843051-DDFAE5AE-C82F-4886-A1CB-1F6490EF2B85Q42007201-800F0CF8-408F-44AD-968B-C817272313B4Q42462435-60885166-1366-4759-AE7B-035E35366EC8Q42517287-14DF82C1-4269-41AA-B855-3B0AEB533C4EQ42983026-0FA52D63-31F3-4423-91BF-8A778E30D5B3Q43969556-162B7B8C-E6F5-4B89-9A16-A204249A2746Q45092492-1285E097-8CCE-418A-BF85-2A382807E238Q46572843-8ED98DFC-D209-4D55-8246-FC46A39B4A5EQ46662773-C84E6B30-3376-4D9F-8281-0A7AA91F5845Q47881759-C9B332D7-5039-47BC-A48F-462DF840B21FQ53532964-3FF92186-24CA-4BC0-8D4D-96842983F526Q53563511-CB4801DA-078A-4153-A97E-7A39820FE869Q54422518-2F34D236-4A98-40A1-8ED0-E49CF1B91C2C
P2860
Tryptase activates the mitogen-activated protein kinase/activator protein-1 pathway in human peripheral blood eosinophils, causing cytokine production and release.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Tryptase activates the mitogen ...... tokine production and release.
@en
type
label
Tryptase activates the mitogen ...... tokine production and release.
@en
prefLabel
Tryptase activates the mitogen ...... tokine production and release.
@en
P2093
P1476
Tryptase activates the mitogen ...... tokine production and release.
@en
P2093
Boris Kantor
Francesca Levi-Schaffer
Mor-Li Hartman
Vivian Weg
Vladislav Temkin
P304
P356
10.4049/JIMMUNOL.169.5.2662
P407
P577
2002-09-01T00:00:00Z