Amino acids and Ca2+ stimulate different patterns of Ca2+ oscillations through the Ca2+-sensing receptor.
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Structural mechanism of ligand activation in human calcium-sensing receptor.L-histidine sensing by calcium sensing receptor inhibits voltage-dependent calcium channel activity and insulin secretion in β-cells.Calcium signaling regulates trafficking of familial hypocalciuric hypercalcemia (FHH) mutants of the calcium sensing receptor.Mechanisms of multimodal sensing by extracellular Ca(2+)-sensing receptors: a domain-based survey of requirements for binding and signallingAmino acid sensing by enteroendocrine STC-1 cells: role of the Na+-coupled neutral amino acid transporter 2.Crosstalk between insulin receptor and G protein-coupled receptor signaling systems leads to Ca²+ oscillations in pancreatic cancer PANC-1 cells.Role of Ca2+ and L-Phe in regulating functional cooperativity of disease-associated "toggle" calcium-sensing receptor mutations.Extracellular calcium sensing receptor stimulation in human colonic epithelial cells induces intracellular calcium oscillations and proliferation inhibitionDirect determination of multiple ligand interactions with the extracellular domain of the calcium-sensing receptor.Oxygen-sensing pathways and the development of mammalian gas exchange.ERK signaling mediates CaSR-promoted axon growth.Intracellular Ca(2+) oscillations generated via the extracellular Ca(2+)-sensing receptor (CaSR) in response to extracellular Ca(2+) or L-phenylalanine: Impact of the highly conservative mutation Ser170ThrCalcium as an extracellular signalling molecule: perspectives on the Calcium Sensing Receptor in the brain.Developmental origins of obesity: a sympathoadrenal perspective.Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552Mitogenic signaling pathways induced by G protein-coupled receptors.FGF9-induced proliferative response to eosinophilic inflammation in oesophagitis.Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888Identification of an L-phenylalanine binding site enhancing the cooperative responses of the calcium-sensing receptor to calcium.Behind the curtain: cellular mechanisms for allosteric modulation of calcium-sensing receptors.Amino acid-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor are mediated by a phospholipase C/inositol 1,4,5-trisphosphate-independent pathway that requires G12, Rho, filamin-A, and the actin cytoskeleton.Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR PROTEIN KINASE D (PKD).Effectors of the frequency of calcium oscillations in HEK-293 cells: wavelet analysis and a computer model.Allosteric modulation of the calcium-sensing receptor.Allosteric activation of the extracellular Ca2+-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation.Requirement of the TRPC1 cation channel in the generation of transient Ca2+ oscillations by the calcium-sensing receptor.Increased receptor stimulation elicits differential calcium-sensing receptor(T888) dephosphorylation.Termination of cAMP signals by Ca2+ and G(alpha)i via extracellular Ca2+ sensors: a link to intracellular Ca2+ oscillations.A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing.Homology modeling of the transmembrane domain of the human calcium sensing receptor and localization of an allosteric binding site.Calcium sensing receptor activation by a calcimimetic suggests a link between cooperativity and intracellular calcium oscillations.Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides: inhibition of PTH secretion, suppression of intracellular cAMP levels, and a common mechanism of action with L-amino acids.The combined impact of plant-derived dietary ingredients and acute stress on the intestinal arachidonic acid cascade in Atlantic salmon (Salmo salar).Cardiac microvascular endothelial cells express a functional Ca+ -sensing receptor.Cardiopulmonary effects of chronic administration of the NO synthase inhibitor L-NAME in the chick embryo.Ca2+-sensing receptor induces Rho kinase-mediated actin stress fiber assembly and altered cell morphology, but not in response to aromatic amino acids.
P2860
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P2860
Amino acids and Ca2+ stimulate different patterns of Ca2+ oscillations through the Ca2+-sensing receptor.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Amino acids and Ca2+ stimulate ...... ugh the Ca2+-sensing receptor.
@en
type
label
Amino acids and Ca2+ stimulate ...... ugh the Ca2+-sensing receptor.
@en
prefLabel
Amino acids and Ca2+ stimulate ...... ugh the Ca2+-sensing receptor.
@en
P2860
P1476
Amino acids and Ca2+ stimulate ...... ugh the Ca2+-sensing receptor.
@en
P2093
Enrique Rozengurt
Steven H Young
P2860
P304
P356
10.1152/AJPCELL.00432.2001
P577
2002-06-01T00:00:00Z